D
David Sayre
Researcher at Stony Brook University
Publications - 60
Citations - 5336
David Sayre is an academic researcher from Stony Brook University. The author has contributed to research in topics: Microscopy & Diffraction. The author has an hindex of 25, co-authored 58 publications receiving 5003 citations. Previous affiliations of David Sayre include University of Pennsylvania & State University of New York System.
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Journal ArticleDOI
Extending the methodology of X-ray crystallography to allow imaging of micrometre-sized non-crystalline specimens
TL;DR: Extending the methodology of X-ray crystallography to allow imaging of micrometre-sized non-crystalline specimens was proposed in this paper, where the authors extended the methodology to allow the imaging of micro-scale specimens.
Journal ArticleDOI
Phase retrieval from the magnitude of the Fourier transforms of nonperiodic objects
TL;DR: The authors' computer phasing experiments accurately retrieved the phase from the magnitude of the Fourier transforms of 2D and 3D complex-valued objects by using positivity constraints on the imaginary part of the objects and loose supports, with the oversampling factor much less than 4 for 2d and 8 for 3D objects.
Journal ArticleDOI
Biological imaging by soft x-ray diffraction microscopy
David A. Shapiro,Pierre Thibault,T. Beetz,T. Beetz,Veit Elser,Malcolm R. Howells,Chris Jacobsen,Chris Jacobsen,Janos Kirz,Janos Kirz,E. Lima,H. Miao,Aaron M. Neiman,David Sayre +13 more
TL;DR: This work represents a previously uncharacterized application of x-ray diffraction microscopy to a specimen of this complexity and provides confidence in the feasibility of the ultimate goal of imaging biological specimens at 10-nm resolution in three dimensions.
Journal ArticleDOI
An assessment of the resolution limitation due to radiation-damage in X-ray diffraction microscopy
Malcolm R. Howells,T. Beetz,Henry N. Chapman,C. Cui,James M. Holton,James M. Holton,Chris Jacobsen,Chris Jacobsen,Janos Kirz,Janos Kirz,E. Lima,Stefano Marchesini,H. Miao,David Sayre,David A. Shapiro,John C. H. Spence,John C. H. Spence,D. Starodub +17 more
TL;DR: The conclusion of this study is that, based on the natural contrast between protein and water and "Rose-criterion" image quality, one should be able to image a frozen-hydrated biological sample using XDM at a resolution of about 10 nm.
ReportDOI
Linac coherent light source (LCLS) conceptual design report
J. Arthur,William Graves,M. Renner,James Rosenzweig,G. Faigel,Zhirong Huang,Michael Wulff,Janos Hajdu,I. Evans,K. Kulander,Andrew Y. Ng,Jianwei Miao,D.H. Dowell,Janos Kirz,David Sayre,P. Ilinski,Roger Falcone,D. Imre,Linda Young,P. Emma,C.V. Robinson,A. Zewail,Phillip Bucksbaum,Otto Landen,Arthur Toor,R.W. Lee,G. Mulhollan,Isaac Vasserman,J.C. Gauthier,Elizabeth Moog,Gennady Stupakov,John Schmerge,Richard Neutze,D. Schneider,D. Dungan,C. Limborg,A.S. Fisher,P.R. Bolton,R. Yotam,L. Klaisner,Heinz-Dieter Nuhn,R. Ruland,R.R. Freeman,Efim Gluskin,Xijie Wang,Alex H. Lumpkin,S. Mochrie,Philip A. Anfinrud,Francesco Sette,Chris Jacobsen,R. Humphry,M. Xie,Mark Woodley,Keith A. Nelson,V. Bharadwaj,J. Galayda,D. Saenz,Emil Trakhtenberg,Luca Serafini,G. Ruocco,Stephen V. Milton,Edgar Weckert,Carl Schroeder,E.I. Lindau,Patrick Krejcik,Richard M. Bionta,S. Sasaki,Roman Tatchyn,D. Nguyen,Jerome B. Hastings,G. Materlik,Ilan Ben-Zvi,Mark Sutton,Ciaran Lewis,Justin Wark,Glenn Decker,David Riley,P.K. Den Hartog,Claudio Pellegrini,Dennis Palmer,S. Dierker,M. Ferrario,S. K. Sinha,R. C. Cauble,Keith O. Hodgson,William M. Fawley,S. J. Rose,D. Waltz,J. M. Paterson,J.C. Frisch,B. Stephenson,R.E. Kirby,Herman Winick,Abraham Szöke,K.J. Kim,A. Wootton,Max Cornacchia,J.E. Clendenin,D. van der Spoel,C.C. Kao,Michael Borland,Sven Reiche,Nikolay Vinokurov,S. M. Gierman,Patrick Audebert,Karl Bane +105 more
TL;DR: The Linac Coherent Light Source (LCLS) as mentioned in this paper is a free-electron-laser (FEL) R&D facility operating in the wavelength range 1.5-15 angstrom, which utilizes the SLAC linac and produces sub-picosecond pulses of short wavelength x-rays with very high peak brightness and full transverse coherence.