D
David Speicher
Researcher at McMaster University
Publications - 37
Citations - 2442
David Speicher is an academic researcher from McMaster University. The author has contributed to research in topics: Population & Internal medicine. The author has an hindex of 12, co-authored 34 publications receiving 1280 citations. Previous affiliations of David Speicher include Griffith University & University of Queensland.
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Journal ArticleDOI
CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database
Brian Alcock,Amogelang R. Raphenya,Tammy T. Y. Lau,Kara K. Tsang,Mégane Bouchard,Arman Edalatmand,William Huynh,Anna-Lisa V. Nguyen,Annie A. Cheng,Sihan Liu,Sally Y. Min,Anatoly Miroshnichenko,Hiu-Ki R Tran,Rafik El Werfalli,Jalees A. Nasir,Martins Oloni,David Speicher,Alexandra Florescu,Bhavya Singh,Mateusz Faltyn,Anastasia Hernández-Koutoucheva,Arjun N. Sharma,Emily Bordeleau,Andrew C. Pawlowski,Haley L. Zubyk,Damion M. Dooley,Emma Griffiths,Finlay Maguire,Geoffrey L. Winsor,Robert G. Beiko,Fiona S. L. Brinkman,William W. L. Hsiao,William W. L. Hsiao,Gary Van Domselaar,Gary Van Domselaar,Andrew G. McArthur +35 more
TL;DR: A new Resistomes & Variants module provides analysis and statistical summary of in silico predicted resistance variants from 82 pathogens and over 100 000 genomes, able to summarize predicted resistance using the information included in CARD, identify trends in AMR mobility and determine previously undescribed and novel resistance variants.
Journal ArticleDOI
Evidence of human coronavirus HKU1 and human bocavirus in Australian children
Theo P. Sloots,P. McErlean,P. McErlean,David Speicher,David Speicher,Katherine E. Arden,Katherine E. Arden,Michael D. Nissen,Ian M. Mackay,Ian M. Mackay +9 more
TL;DR: Children under the age of 2 years were most at risk of infection by these viruses which contribute significantly to the microbial burden among patients with respiratory tract disease during the colder months.
Journal ArticleDOI
Emerging role of bacteria in oral carcinogenesis: a review with special reference to perio-pathogenic bacteria
TL;DR: A critical analysis of and an update on the association between bacteria and oral carcinogenesis and the possible mechanisms underlying it are provided.
Journal ArticleDOI
Inflammatory Bacteriome and Oral Squamous Cell Carcinoma
Manosha Perera,Nezar Noor Al-hebshi,Irosha Perera,Deepak S. Ipe,Glen C. Ulett,David Speicher,David Speicher,David Speicher,Tsute Chen,Newell W. Johnson,Newell W. Johnson +10 more
TL;DR: Functionally, proinflammatory bacterial attributes, including lipopolysaccharide biosynthesis and peptidases, were enriched in the OSCC tissues, substantiating evidence for the inflammatory nature of the bacteriome associated with OSCC.
Journal ArticleDOI
A dysbiotic mycobiome dominated by Candida albicans is identified within oral squamous-cell carcinomas.
Manosha Perera,Nezar Noor Al-hebshi,Irosha Perera,Deepak S. Ipe,Glen C. Ulett,David Speicher,Tsute Chen,Newell W. Johnson +7 more
TL;DR: A dysbiotic mycobiome dominated by C. albicans was found in association with oral squamous-cell carcinoma, a finding worth further investigation.