D
David Spiegel
Researcher at Stanford University
Publications - 838
Citations - 50967
David Spiegel is an academic researcher from Stanford University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 106, co-authored 733 publications receiving 46276 citations. Previous affiliations of David Spiegel include Tel Aviv University & University of Adelaide.
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Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death
Marie-Julie Nokin,Florence Durieux,Justine Bellier,Olivier Peulen,Koji Uchida,David Spiegel,James R. Cochrane,Craig A. Hutton,Vincenzo Castronovo,Akeila Bellahcene +9 more
TL;DR: This study explored MG-mediated dicarbonyl stress status in four breast and glioblastoma cancer cell lines in relation with their glycolytic phenotype and MG detoxifying capacity and showed that low doses of MG induced AGEs formation and tumour growth in vivo can be reversed using a MG scavenger.
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Circadian disruption and biomarkers of tumor progression in breast cancer patients awaiting surgery
Elizabeth Cash,Sandra E. Sephton,Anees B. Chagpar,David Spiegel,Whitney N. Rebholz,Lauren A. Zimmaro,Jean M. Tillie,Firdaus S. Dhabhar +7 more
TL;DR: The results raise the possibility that, among patients with active breast tumors, disruption of circadian activity rhythms and elevated CAR may facilitate tumor promotion and progression.
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Hemodialysis urea rebound: The effect of increasing dialysis efficiency
TL;DR: It is concluded that increasing dialysis efficiency increases urea rebound and increases the error in Kt/V determinations from single pool urea kinetics.