Deann T. Snyder

TL;DR: Using global phylogenomics, this article showed that mutations frequently occur in the C-terminal end of ORF7a, which negates anti-immune activities of the protein, which results in elevated type I interferon response to the viral infection.

TL;DR: The data suggest that SLC11A1 has a heretofore unknown role in activation of a large subset of innate lymphocytes that are critical sources of IFN-γ.

TL;DR: This study validated and compared two protocols for inactivating SARS-CoV-2: heat treatment and ultraviolet irradiation, and outlined the strengths and weaknesses of each method so that investigators might choose the one which best meets their research goals.

TL;DR: In this article, heat treatment and ultraviolet irradiation were compared to render the SARS-CoV-2 virus completely incapable of infection while limiting the destructive effects of inactivation, and the results showed that UV irradiation resulted in a 2-log reduction of detectable genomes compared to heat inactivation.

TL;DR: This review focuses on type I IFN induction and downstream consequences during infection with the following intracellular bacteria: Chlamydia trachomatis, Listeria monocytogenes, Mycobacterium tuberculosis, Salmonella enterica serovar Typhimurium, Francisella tularensis, Brucella abortus, Legionella pneumophila, and Coxiella burnetii.