Debbie A Lawlor

TL;DR: Genetic inhibition of PCSK9 results in similar metabolic effects as statin therapy across a detailed lipid and metabolite profile, which could potentially translate into subtle differences in cardiovascular risk reduction.

TL;DR: In this paper, the authors used data from the index generation of the Avon Longitudinal Study of Parents and Children (young people aged 26-29) to examine anxiety at the beginning of the COVID-19 pandemic and again once restrictions were eased (June 2020) and compared these to two pre-pandemic assessments of anxiety measured 2013/2014 and 2015/17.

TL;DR: This paper examined the association between external locus of control and negative cognitive styles in adolescence with odds of depression in 4,301 young adults using logistic regression models unadjusted and adjusted for potential confounding factors.

TL;DR: In this paper, the authors examined annual US natality, Centers for Disease Control and Prevention IVF cycle activity and live birth data from 1999 to 2018 encompassing 3,286,349 treatment cycles, to estimate the age-stratified reduction in IVF cycles undertaken after the 2008 financial recession, with forward quantitative modelling of fertility cycle activity, and cumulative live births for 2020 to 2023, with women younger than 35 years overall undertaking 22,504 (95% CI 14,320 to 30,690) fewer cycles.

TL;DR: In this article, a two-sample Mendelian randomization (MR) using summary data on associations between genotype B12 (10 genetic variants) or genotype-folate (four genetic variants), was performed to investigate whether this relationship is causal.