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Debbie Chachra

Bio: Debbie Chachra is an academic researcher from Franklin W. Olin College of Engineering. The author has contributed to research in topics: Engineering education & Fluoride. The author has an hindex of 18, co-authored 57 publications receiving 1345 citations. Previous affiliations of Debbie Chachra include University of Toronto & Mount Sinai Hospital, Toronto.


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TL;DR: The authors found that engineering students are typical of students in other majors with respect to: persistence in major; persistence by gender and ethnicity; racial/ethnic distribution; and grade distribution, concluding that engagement is a precursor to persistence.
Abstract: Records from the Multiple-Institution Database for Investigating Engineering Longitudinal Development indicate that engineering students are typical of students in other majors with respect to: persistence in major; persistence by gender and ethnicity; racial/ethnic distribution; and grade distribution. Data from the National Survey of Student Engagement show that this similarity extends to engagement outcomes including course challenge, faculty interaction, satisfaction with institution, and overall satisfaction. Engineering differs from other majors most notably by a dearth of female students and a low rate of migration into the major. Noting the similarity of students of engineering and other majors with respect to persistence and engagement, we propose that engagement is a precursor to persistence. We explore this hypothesis using data from the Academic Pathways Study of the Center for the Advancement of Engineering Education. Further exploration reveals that although persistence and engagement do not vary as much as expected by discipline, there is significant institutional variation, and we assert a need to address persistence and engagement at the institutional level and throughout higher education. Finally, our findings highlight the potential of making the study of engineering more attractive to qualified students. Our findings suggest that a two-pronged approach holds the greatest potential for increasing the number of students graduating with engineering degrees: identify programming that retains the students who come to college committed to an engineering major, and develop programming and policies that allow other students to migrate in. There is already considerable discourse on persistence, so our findings suggest that more research focus is needed on the pathways into engineering, including pathways from other majors.

458 citations

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TL;DR: This paper found that parental and high school mentor influences as a motivation to study engineering, as well as confidence in math and science skills, were identified as correlates of persistence and intention to complete an engineering major was also a correlate of persistence; it appears to decline sharply at least two semesters prior to students leaving engineering.
Abstract: BACKGROUND Understanding more about student decisions to leave engineering may lead to higher retention. This study builds on the literature and focuses on the experiences of a cohort of students who aimed to complete their undergraduate work in 2007. PURPOSE (HYPOTHESIS) This paper presents the outcomes of the longitudinal administration of the Persistence in Engineering survey. The goal was to identify correlates of persistence in undergraduate engineering education and professional engineering practice. DESIGN/METHOD The survey was administered seven times over four years to a cohort of students who had expressed interest in studying engineering. At the end of the study, the participants were categorized as persisters or non-persisters. Repeated measures analysis of variance was used, in conjunction with other approaches, to test for differences between the groups. RESULTS Persisters and non-persisters did not differ significantly according to the majority of the constructs. Nevertheless, parental and high school mentor influences as a motivation to study engineering, as well as confidence in math and science skills, were identified as correlates of persistence. Intention to complete an engineering major was also a correlate of persistence; it appears to decline sharply at least two semesters prior to students leaving engineering. The findings also suggest that there might be differences among non-persisters when they are further grouped by when they leave engineering. CONCLUSIONS Facilitating higher levels of mentor involvement before college might increase student motivation to study engineering, and also constitute a mechanism for fostering confidence in math and science skills. Since the intention to complete an engineering degree decreases well before students act, there may be opportunities for institutions to develop targeted interventions for students, and help them make informed decisions.

166 citations

Journal ArticleDOI
TL;DR: Fluoride's effects on bone mass and bone turnover were not mediated by PTH, and IGF-1 was increased by fluoride and was associated with increased bone turnover, but was not correlated with bone formation markers.
Abstract: We hypothesized that fluoride partly acts by changing the levels of circulating calcium-regulating hormones and skeletal growth factors. The effects of oral fluoride on 24 female, Dutch-Belted, young adult rabbits were studied. The rabbits were divided into two study groups, one control and the other receiving about 16 mg fluoride/rabbit/day in their drinking water. After 6 months of fluoride dosing, all rabbits were euthanized and bone and blood samples were taken for analyses. Fluoride treatment increased serum and bone fluoride levels by over an order of magnitude (P 0.4). BAP was increased 37% (P < 0.05) by fluoride; serum TRAP was increased 42% (P < 0.05); serum IGF-1 was increased 40% (P < 0.05). Fluoride increased the vertebral BV/TV by 35% (P < 0.05) and tibial ash weight by 10% (P < 0.05). However, the increases in bone mass and bone formation were not reflected in improved bone strength. Fluoride decreased bone strength by about 19% in the L5 vertebra (P < 0.01) and 25% in the femoral neck (P < 0.05). X-ray diffraction showed altered mineral crystal thickness in fluoride-treated bones (P < 0.001), and there was a negative association between crystal width and fracture stress of the femur (P < 0.02). In conclusion, fluoride's effects on bone mass and bone turnover were not mediated by PTH. IGF-1 was increased by fluoride and was associated with increased bone turnover, but was not correlated with bone formation markers. High-dose fluoride treatment did not improve, but decreased, bone strength in rabbits, even in the absence of impaired mineralization.

69 citations

24 Jun 2007
TL;DR: This article found that non-persisters are more likely to be motivated to study engineering by external (family) influences, are less confident in their math and science skills, and less engaged in their studies than persisters.
Abstract: A knowledge of the differences between persisters and nonpersisters may aid in the design of engineering curricula as well as strategies for academic advising. In the preliminary stage of analysis, as reported in this paper, the differences between persisters and non-persisters in engineering are apparent in the freshmen and sophomore years. In general, non-persisters are more likely to be motivated to study engineering by external (family) influences, are less confident in their math and science skills, and less likely to be engaged in their studies than persisters.

55 citations

Journal ArticleDOI
TL;DR: The effect of high doses of fluoride on the strength and stiffness of bone may be mediated by its effect on bone mineral, which suggests that the mechanical properties of bone were adversely affected.
Abstract: Fluoride therapy has been used clinically for many years, but its use remains controversial and many basic questions remain unanswered. Accordingly, this study returns to an animal model to study the effects of high doses of fluoride on bone mineral in rabbits. Twelve rabbits, aged 3(1/2) months at the start of the study, received drinking water fluoridated at 100 ppm while their 12 control counterparts drank distilled water. All rabbits were sacrificed after 6 months. Fluoride was readily incorporated into femoral cortical bone (7473 +/- 966 ppm F versus 1228 +/- 57 ppm in controls; P < 0.00005). Fluoride therapy led to increased mineralization, as measured by density fractionation (P < 0.0005 for the distributions). The bone mineral itself was altered, with a significant increase in the width of crystals (66.2 +/- 2.0 A versus 61.2 +/- 0.9 A; P < 0.01). The microhardness of both cortical and cancellous bone in the femoral head of fluoride-treated rabbits was greater than that in the controls (P < 0.05). The phosphate, calcium, and carbonate contents in the bone was the same in both groups. Finally, fluoride administration did not affect the architecture or connectivity of cancellous bone in the femoral head. Previously published data [1] indicated that the mechanical properties of bone were adversely affected; this suggests that the effect of high doses of fluoride on the strength and stiffness of bone may be mediated by its effect on bone mineral.

55 citations


Cited by
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Journal Article
TL;DR: This study reviews several of the most commonly used inductive teaching methods, including inquiry learning, problem-based learning, project-basedLearning, case-based teaching, discovery learning, and just-in-time teaching, and defines each method, highlights commonalities and specific differences, and reviews research on the effectiveness.
Abstract: Traditional engineering instruction is deductive, beginning with theories and progressing to the applications of those theories Alternative teaching approaches are more inductive Topics are introduced by presenting specific observations, case studies or problems, and theories are taught or the students are helped to discover them only after the need to know them has been established This study reviews several of the most commonly used inductive teaching methods, including inquiry learning, problem-based learning, project-based learning, case-based teaching, discovery learning, and just-in-time teaching The paper defines each method, highlights commonalities and specific differences, and reviews research on the effectiveness of the methods While the strength of the evidence varies from one method to another, inductive methods are consistently found to be at least equal to, and in general more effective than, traditional deductive methods for achieving a broad range of learning outcomes

1,673 citations

Journal ArticleDOI
TL;DR: A wide range of natural-origin polymers with special focus on proteins and polysaccharides that are being used in research, or might be potentially useful as carriers systems for active biomolecules or as cell carriers with application in the tissue engineering field targeting several biological tissues are overviewed.

1,269 citations

Journal ArticleDOI
TL;DR: There is an essential relation between poverty and fluorosis as malnutrition is found to play an aggressive role in its severity, as the lack of access to clean water denies the most essential of all rights, the right to life.
Abstract: ‘Water is life,’ so central to human life, yet over one billion people across the world have no access to safe drinking water. Of late, there has been increasing global attention focused on resolving water quality problems especially in developing countries, as the lack of access to clean water denies the most essential of all rights, the right to life. The latest estimates suggest that around 200 million people, from among 25 nations the world over, are under the dreadful fate of fluorosis. India and China, the two most populous countries of the world, are the worst affected. India is plagued with numerous water quality problems due to prolific contaminants mainly of geogenic origin and fluoride stands first among them. The weathering of primary rocks and leaching of fluoride-containing minerals in soils yield fluoride rich groundwater in India which is generally associated with low calcium content and high bicarbonate ions. The unfettered ground water tapping exacerbates the failure of drinking water so...

1,116 citations

Journal ArticleDOI
TL;DR: Despite significant advances in the area of cardiovascular prostheses, there has yet to be developed a completely biocompatible, long-lasting implant and the possibility of applying selective cell seeding to naturally derived bioprosthetics moves us closer to a living tissue replacement.

773 citations