D
Deborah Commins
Researcher at University of Southern California
Publications - 38
Citations - 1450
Deborah Commins is an academic researcher from University of Southern California. The author has contributed to research in topics: Acquired immunodeficiency syndrome (AIDS) & Meningioma. The author has an hindex of 19, co-authored 38 publications receiving 1278 citations. Previous affiliations of Deborah Commins include University of California, Los Angeles.
Papers
More filters
Journal ArticleDOI
Review of meningioma histopathology
TL;DR: It is hoped that an understanding of the genetic changes that underlie tumor progression will improve healthcare professionals' ability to predict the behavior of meningiomas.
Journal ArticleDOI
The National NeuroAIDS Tissue Consortium Brain Gene Array: Two Types of HIV-Associated Neurocognitive Impairment
Benjamin B. Gelman,Tiansheng Chen,Joshua G. Lisinicchia,Vicki M. Soukup,J. Russ Carmical,Jonathan M. Starkey,Eliezer Masliah,Deborah Commins,Dianne Brandt,Igor Grant,Elyse J. Singer,Andrew J. Levine,Jeremy A. Miller,Jessica M. Winkler,Howard S. Fox,Bruce A. Luxon +15 more
TL;DR: Two patterns of brain gene expression suggest that more than one pathophysiological process occurs in HIV-1-associated neurocognitive impairment, and array results suggest that modulation of transvascular signaling is a potentially promising approach.
Journal ArticleDOI
Human immunodeficiency virus type 1 in the central nervous system leads to decreased dopamine in different regions of postmortem human brains.
Adarsh M. Kumar,J. B. Fernandez,Elyse J. Singer,Deborah Commins,Drenna Waldrop-Valverde,Raymond L. Ownby,Mahendra Kumar +6 more
TL;DR: Findings suggest widespread deficits in dopamine in different brain regions of HIV-1-infected cases, and that these deficits may be the results of HIV -1-induced neurodegeneration in the subcortical regions of human brain.
Journal ArticleDOI
HIV DNA Is Frequently Present within Pathologic Tissues Evaluated at Autopsy from Combined Antiretroviral Therapy-Treated Patients with Undetectable Viral Loads
Susanna L. Lamers,Rebecca Rose,Ekaterina Maidji,Melissa Agsalda-Garcia,David J. Nolan,Gary B. Fogel,Marco Salemi,Debra Leiolani Garcia,Paige M. Bracci,William H. Yong,Deborah Commins,Jonathan W. Said,Negar Khanlou,Charles H. Hinkin,Miguel Valdes Sueiras,Glenn E. Mathisen,Suzanne M. Donovan,Bruce Shiramizu,Cheryl A. Stoddart,Michael S. McGrath,Elyse J. Singer +20 more
TL;DR: It is substantiated that tissue-associated HIV is present despite cART and can inform future studies into HIV persistence, and additional studies are needed to determine if the HIV recovered from tissues promotes the pathogenesis of inflammatory diseases, such as HIV-associated neurocognitive disorders, cancer, and atherosclerosis.
Journal ArticleDOI
Neurovirological correlation with HIV-associated neurocognitive disorders and encephalitis in a HAART-era cohort
Benjamin B. Gelman,Joshua G. Lisinicchia,Susan Morgello,Eliezer Masliah,Deborah Commins,Cristian L. Achim,Howard S. Fox,Dennis L. Kolson,Igor Grant,Elyse J. Singer,Constantin T. Yiannoutsos,Seth Sherman,Gary Gensler,David J. Moore,Tiansheng Chen,Vicki M. Soukup +15 more
TL;DR: Brain HIV RNA and to a lesser extent HIV DNA are correlated with worse NP performance in the 6 months before death, and these patients could obtain added NP improvement by further reducing brain HIV while on HAART.