D
Deborah J. Cook
Researcher at McMaster University
Publications - 942
Citations - 165225
Deborah J. Cook is an academic researcher from McMaster University. The author has contributed to research in topics: Intensive care & Randomized controlled trial. The author has an hindex of 173, co-authored 907 publications receiving 148928 citations. Previous affiliations of Deborah J. Cook include McMaster University Medical Centre & Queen's University.
Papers
More filters
Journal ArticleDOI
Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients
Mette Krag,Anders Perner,Jørn Wetterslev,Matt P. Wise,Mark Borthwick,Stepani Bendel,Colin McArthur,Deborah J. Cook,Niklas Nielsen,Paolo Pelosi,Frederik Keus,Anne Berit Guttormsen,Alma D Moller,Morten Hylander Møller +13 more
TL;DR: Clinically important GI bleeding was not associated with increased adjusted 90-day mortality, which largely can be explained by severity of comorbidity, other organ failures and age.
Journal ArticleDOI
Randomized trial of combination versus monotherapy for the empiric treatment of suspected ventilator-associated pneumonia.
TL;DR: For critically ill patients who have suspected late ventilator-associated pneumonia and who are at low risk for difficult-to-treat Gram-negative bacteria, monotherapy is associated with similar outcomes compared with combination therapy and combination therapy is safe and may be associated with better microbiological and clinical outcomes.
Journal ArticleDOI
Rationing in the intensive care unit.
Robert D. Truog,Dan W. Brock,Deborah J. Cook,Marion Danis,John M. Luce,Gordon D. Rubenfeld,Mitchell M. Levy +6 more
TL;DR: A taxonomy of the rationing choices faced by intensivists is developed as a framework for ethical analysis and clarifies the type of evidence appropriate to supporting the decision that is made.
Journal ArticleDOI
Users' guides to the medical literature XVI. How to use a treatment recommendation
TL;DR: This work proposes a hierarchy of rigor of recommendations to guide clinicians when judging the usefulness of particular recommendations, and in an era in which clinicians are barraged by recommendations as to how to manage their patients, this hierarchy provides a potentially useful set of guides.
Journal ArticleDOI
Adaptation to the Intensive Care Environment (ATICE): Development and validation of a new sedation assessment instrument
Bernard De Jonghe,Deborah J. Cook,Lauren Griffith,Corinne Appéré-De-Vecchi,Gordon H. Guyatt,Valerie Théron,Annick Vagnerre,Hervé Outin +7 more
TL;DR: The ATICE measures the adaptation of mechanically ventilated patients to the ICU environment and demonstrates high reliability, validity, and responsiveness of this instrument.