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Deborah J. Cook
Researcher at McMaster University
Publications - 942
Citations - 165225
Deborah J. Cook is an academic researcher from McMaster University. The author has contributed to research in topics: Intensive care & Randomized controlled trial. The author has an hindex of 173, co-authored 907 publications receiving 148928 citations. Previous affiliations of Deborah J. Cook include McMaster University Medical Centre & Queen's University.
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Journal ArticleDOI
Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acute respiratory distress syndrome. Pressure- and Volume-Limited Ventilation Strategy Group.
Thomas E. Stewart,Maureen O. Meade,Deborah J. Cook,John Granton,R. V. Hodder,Stephen E. Lapinsky,C. D. Mazer,R. F. Mclean,T. S. Rogovein,B. D. Schouten,T. R. J. Todd,Arthur S. Slutsky +11 more
TL;DR: In patients at high risk for the acute respiratory distress syndrome, a strategy of mechanical ventilation that limits peak inspiratory pressure and tidal volume does not appear to reduce mortality and may increase morbidity.
Journal ArticleDOI
Hypoglycemia and risk of death in critically ill patients.
Simon Finfer,Bette Liu,Dean R. Chittock,Robyn Norton,John Myburgh,Colin McArthur,Imogen Mitchell,Denise Foster,Vinay Dhingra,William R. Henderson,Juan J. Ronco,Rinaldo Bellomo,Deborah J. Cook,Ellen McDonald,Peter Dodek,Paul C. Hébert,Daren K. Heyland,Bruce G. Robinson +17 more
TL;DR: In critically ill patients, intensive glucose control leads to moderate and severe hypoglycemia, both of which are associated with an increased risk of death, and the association exhibits a dose-response relationship and is strongest for death from distributive shock.
Journal ArticleDOI
Users' Guides to the Medical Literature: VI. How to Use an Overview
Andrew D Oxman,Deborah J. Cook,Gordon H. Guyatt,Eric Bass,Patrick Brill-Edwards,George P. Browman,Allan S. Detsky,Michael E. Farkouh,Hertzei Gerstein,Ted Haines,Brian Haynes,Robert Hayward,Anne Holbrook,Roman Jaeschke,Elizabeth F. Juniper,Andreas Laupacis,Hui Lee,Mitchell Levine,Virginia Moyer,David Naylor,Jim Nishikawa,Ameen Patel,John Philbrick,Scott Richardson,Stephane Sauve,David Sacked,Jack Sinclair,Brian L. Strom,K. S. Trout,Sean Tunis,Stephen D. Walter,John W Williams,Mark C. Wilson +32 more
TL;DR: A 55-year-old man has had his serum cholesterol level measured at a shopping mall 2 months ago and his cholesterol level was elevated, but before deciding on a treatment recommendation, you elect to find out just how big a reduction in the risk of CHD this patient could expect from a cholesterollowering diet or drug therapy.
Journal ArticleDOI
Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary disease.
TL;DR: A meta-analysis of randomised controlled trials of respiratory rehabilitation in patients with COPD found that it relieves dyspnoea and improves the control over COPD, and the value of the improvement in exercise capacity is not clear.
Journal ArticleDOI
Myocardial Injury after Noncardiac Surgery: A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes
Fernando Botto,Pablo Alonso-Coello,Matthew T. V. Chan,Matthew T. V. Chan,Juan Carlos Villar,Denis Xavier,Sadeesh Srinathan,Gordon H. Guyatt,Patricia Cruz,Patricia Cruz,Michelle M. Graham,Michelle M. Graham,Chew Yin Wang,Otavio Berwanger,R.M. Pearse,R.M. Pearse,Bruce M Biccard,Valsa Abraham,Germán Málaga,Germán Málaga,Graham S. Hillis,Graham S. Hillis,Reitze N. Rodseth,Deborah J. Cook,Deborah J. Cook,Deborah J. Cook,Carisi Anne Polanczyk,Wojciech Szczeklik,Daniel I. Sessler,Daniel I. Sessler,Tej Sheth,Tej Sheth,Gareth L Ackland,Gareth L Ackland,Martin Leuwer,Amit X Garg,Amit X Garg,Yannick LeManach,Yannick LeManach,Shirley Pettit,Diane Heels-Ansdell,Giovanna Luratibuse,Giovanna Luratibuse,Michael Walsh,Michael Walsh,Robert Sapsford,Holger J Schünemann,Holger J Schünemann,Andrea Kurz,Andrea Kurz,Sabu Thomas,Marko Mrkobrada,Marko Mrkobrada,Lehana Thabane,Hertzel C. Gerstein,Pilar Paniagua,Pilar Paniagua,Peter Nagele,Peter Nagele,Parminder Raina,Salim Yusuf,Salim Yusuf,Salim Yusuf,Philip J. Devereaux,Philip J. Devereaux,Matthew J. McQueen,Mohit Bhandari,Jackie Bosch,Norman Buckley,Clara K Chow,Richard Halliwell,Stephen Li,Vincent W. Lee,J. Mooney,Mariana Vargas Furtado,Erica Aranha Suzumura,Eliana Vieira Santucci,Katia R. M. Leite,Jose Amalth do Espirirto Santo,César A. Jardim,Alexandre Biasi Cavalcanti,Hélio Penna Guimarães,Michael J Jacka,Finlay A. McAlister,Sean McMurtry,Derek R. Townsend,Neesh Pannu,Sean M. Bagshaw,Amal Bessissow,Emmanuelle Duceppe,John W. Eikelboom,Javier Ganame,James Hankinson,Stephen Hill,Sanjit S. Jolly,Andre Lamy,Elizabeth Ling,Patrick Magloire,Guillaume Paré,Deven Reddy,David Szalay,Jacques G. Tittley,Jeff Weitz,Richard P. Whitlock,Saeed Darvish-Kazim,Justin DeBeer,Peter A. Kavsak,Clive Kearon,Richard Mizera,Martin O'Donnell,Matthew B. McQueen,Jehonathan H. Pinthus,Sebastian Ribas,Marko Simunovic,Vikas Tandon,Tomas VanHelder,Mitchell Winemaker,Sarah D. McDonald,Paul M. O'Bryne,Ameen Patel,James Paul,Zubin Punthakee,Karen Raymer,Omid Salehian,Frederick A. Spencer,Stephen D. Walter,Andrew Worster,Anthony Adili,Catherine M. Clase,Mark Crowther,James D. Douketis,Azim S. Gangji,Paul Jackson,Wendy Lim,Peter Lovrics,Sergio Mazzadi,William Orovan,Jill Rudkowski,Mark Soth,Maria Tiboni,Rey R. Acedillo,Amit Garg,Amit Garg,Ainslie Hildebrand,Ngan N. Lam,Danielle MacNeil,Pavel S Roshanov,Sadeesh K Srinathan,Clare D. Ramsey,Philip St John,Laurel Thorlacius,Faisal Siddiqui,Hilary P Grocott,Andrew McKay,Trevor W R Lee,Ryan J. J. Amadeo,Duane J. Funk,Heather McDonald,James Zacharias,Olga L. Cortés,Maria Stella Chaparro,Skarlett Vásquez,Alvaro Castañeda,Silvia Moreira Ayub Ferreira,Pierre Coriat,Denis Monneret,Jean Pierre Goarin,Cristina Ibanez Esteve,Catherine Royer,Georges Daas,Gordon Y.S. Choi,Tony Gin,Lydia C.W. Lit,Alben Sigamani,Atiya Faruqui,Radhika Dhanpal,Smitha Almeida,Joseph Cherian,Sultana Furruqh,Lalita Afzal,P. George,Shaveta Mala,Holger Schünemann,Holger Schünemann,Paola Muti,Enrico Vizza,Gracie Ong,Marzida Mansor,Alvin S.B. Tan,Ina Ismiarti Shariffuddin,V Vasanthan,Noorjahan Haneem Md Hashim,A. Wahab Undok,Ushananthini Ki,Hou Yee Lai,Wan Azman Ahmad,Azad Hassan Abdul Razack,Vanessa Valderrama-Victoria,Javier D Loza-Herrera,Maria De Los Angeles Lazo,Aida Rotta-Rotta,Barbara Sokołowska,Jacek Musial,Jacek Górka,Paweł Iwaszczuk,Mateusz Kózka,Maciej Chwała,Marcin Raczek,Tomasz Mrowiecki,Bogusz Kaczmarek,B M Biccard,Hussein Cassimjee,Dean Gopalan,Theroshnie Kisten,Aine Mugabi,P. Naidoo,Rubeshan Naidoo,R.N. Rodseth,D.L. Skinner,Alex Torborg,Gerard Urrútia,Mari Luz Maestre,Miquel Santaló,Raúl Gonzalez,Adrià Font,Cecilia Martínez,Xavier Pelaez,Marta De Antonio,José Villamor,Jesús Alvarez García,Maria José Ferré,Ekaterina Popova,Ignacio Garutti,Carmen Fernández,Maria Palencia,Susana Díaz,Teresa Del Castillo,Alberto Varela,Angeles de Miguel,Manuel Muñoz,Patricia Piñeiro,Gabriel Cusati,Maria Del Barrio,Maria José Membrillo,David Orozco,Fidel Reyes,Robert J. Sapsford,Julian H. Barth,Julian Scott,Alistair Hall,Simon J. Howell,Michaela Lobley,Janet Woods,Susannah Howard,Joanne Fletcher,Nikki Dewhirst,C. Williams,A. Rushton,Ingeborg Welters,M Leuwer,Rupert Pearse,Rupert Pearse,G.L. Ackland,G.L. Ackland,Ahsun Khan,Edyta Niebrzegowska,Sally Benton,Andrew Wragg,Andrew Archbold,Amanda Smith,Eleanor McAlees,Cheryl Ramballi,Neil MacDonald,Marta Januszewska,Robert C M Stephens,Anna Reyes,Laura Gallego Paredes,Pervez Sultan,David Cain,John Whittle,Ana Gutierrez del Arroyo,Zhuo Sun,Patrick S Finnegan,Cameron Egan,Hooman Honar,Aram Shahinyan,Krit Panjasawatwong,Alexander Y. Fu,Sihe Wang,Edmunds Reineks,Jane Blood,Megan Kalin,David W. Gibson,Troy S. Wildes,Vascular Events In Noncardiac Surgery Patients Cohort Evaluation (Vision) Investigators +294 more
TL;DR: Among adults undergoing noncardiac surgery, MINS was an independent predictor of 30-day mortality and had the highest population-attributable risk of the perioperative complications.