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Deborah J. Cook
Researcher at McMaster University
Publications - 942
Citations - 165225
Deborah J. Cook is an academic researcher from McMaster University. The author has contributed to research in topics: Intensive care & Randomized controlled trial. The author has an hindex of 173, co-authored 907 publications receiving 148928 citations. Previous affiliations of Deborah J. Cook include McMaster University Medical Centre & Queen's University.
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Journal ArticleDOI
Investigator-led clinical research consortia: the Canadian Critical Care Trials Group.
John C. Marshall,Deborah J. Cook +1 more
TL;DR: This review summarizes the history, activities, approaches, and challenges of the Canadian Critical Care Trials Group, in the conviction that investigator-led groups such as the authors' represent the future of intensive care unit-based research.
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Lowering of Glucose in Critical care: a randomized pilot trial
Joseph McMullin,Jan Brozek,Ellen McDonald,Roman Jaeschke,Diane Heels-Ansdell,Ryan Leppert,Anders Foss,Deborah J. Cook +7 more
TL;DR: In this pilot trial of ICU patients with high illness severity, glucose values were in the 2 target ranges only 40% of the time, using well-accepted initiation and maintenance insulin infusion algorithms.
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Cardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine
Sangeeta Mehta,John Granton,Anthony C. Gordon,Deborah J. Cook,Stephen E. Lapinsky,Gary E. Newton,Kris Bandayrel,Anjuli Little,Chuin Siau,Dieter Ayers,Joel Singer,Terry Ck Lee,Keith R. Walley,Michelle Storms,D. James Cooper,Cheryl L. Holmes,Paul C. Hébert,Jeffrey J. Presneill,James A. Russell +18 more
TL;DR: Troponin elevation is common in adults with septic shock and was not an independent predictor of mortality, and there were no significant differences in troponin, CK, and ECGs in patients treated with vasopressin and norepinephrine.
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A retrospective cohort pilot study to evaluate a triage tool for use in a pandemic
Michael D. Christian,Cindy Hamielec,Neil M. Lazar,Randy S. Wax,Lauren Griffith,Margaret S. Herridge,David Lee,Deborah J. Cook +7 more
TL;DR: The results suggest that the triage protocol can help to direct resources to patients who are most likely to benefit, and help to decrease the demands on critical care resources, thereby making available more resources to treat other critically ill patients.
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Correlates of clinical failure in ventilator-associated pneumonia: insights from a large, randomized trial.
Andrew F. Shorr,Deborah J. Cook,Xuran Jiang,John Muscedere,John Muscedere,Daren K. Heyland,Daren K. Heyland +6 more
TL;DR: Clinical characteristics correlate with eventual outcomes in VAP and it is suggested that clinicians follow these measures and consider integrating them in their decisions as to when to reevaluate persons with VAP who are not improving.