DeeAnn M. Reeder

Bio: DeeAnn M. Reeder is an academic researcher from Bucknell University. The author has contributed to research in topics: Myotis lucifugus & Pseudogymnoascus destructans. The author has an hindex of 28, co-authored 66 publications receiving 9048 citations. Previous affiliations of DeeAnn M. Reeder include National Museum of Natural History & Boston University.

Mammal Species of the World: A Taxonomic and Geographic Reference

Abstract: Wilson and Reeder's Mammal Species of the World is the classic reference book on the taxonomic classification and distribution of the more than 5400 species of mammals that exist today. The third edition includes detailed information on nomenclature and, for the first time, common names. Each concise entry covers type locality, distribution, synonyms, and major reference sources. The systematic arrangement of information indicates evolutionary relationships at both the ordinal and the family level. This indispensable reference work belongs in public and academic libraries throughout the world and on the shelf of every biologist who works with mammals.

Experimental infection of bats with Geomyces destructans causes white-nose syndrome

Abstract: White-nose syndrome (WNS) has caused recent catastrophic declines among multiple species of bats in eastern North America. The disease's name derives from a visually apparent white growth of the newly discovered fungus Geomyces destructans on the skin (including the muzzle) of hibernating bats. Colonization of skin by this fungus is associated with characteristic cutaneous lesions that are the only consistent pathological finding related to WNS. However, the role of G. destructans in WNS remains controversial because evidence to implicate the fungus as the primary cause of this disease is lacking. The debate is fuelled, in part, by the assumption that fungal infections in mammals are most commonly associated with immune system dysfunction. Additionally, the recent discovery that G. destructans commonly colonizes the skin of bats of Europe, where no unusual bat mortality events have been reported, has generated further speculation that the fungus is an opportunistic pathogen and that other unidentified factors are the primary cause of WNS. Here we demonstrate that exposure of healthy little brown bats (Myotis lucifugus) to pure cultures of G. destructans causes WNS. Live G. destructans was subsequently cultured from diseased bats, successfully fulfilling established criteria for the determination of G. destructans as a primary pathogen. We also confirmed that WNS can be transmitted from infected bats to healthy bats through direct contact. Our results provide the first direct evidence that G. destructans is the causal agent of WNS and that the recent emergence of WNS in North America may represent translocation of the fungus to a region with a naive population of animals. Demonstration of causality is an instrumental step in elucidating the pathogenesis and epidemiology of WNS and in guiding management actions to preserve bat populations against the novel threat posed by this devastating infectious disease.

Stress in free-ranging mammals: integrating physiology, ecology, and natural history

Abstract: We review developments in the study of stress in free-ranging mammals and summarize the physiological and behavioral components of the stress response. Both the sympathetic nervous system response and the regulation and reactivity of the hypothalamic–pituitary–adrenal (HPA) axis are discussed. In particular, we describe how the activity of the HPA axis at baseline levels follows circadian and circannual rhythms in ways that allow animals to respond to predictable environmental changes, focusing largely on the endpoint of this axis, the glucocorticoid hormones cortisol and corticosterone. Superimposed upon these rhythms are the elevated glucocorticoid levels characteristic of the stress response, which allow an animal to respond to unpredictable social, physical, or environmental challenges. Methods used to explore the stress response in free-ranging mammals are described. Both inter- and intraspecific variation in the stress response as they relate to the environment are discussed. Finally, how the regulation and reactivity of the HPA axis varies by life-history stage and sex in mammals is reviewed, focusing on reproduction and development.

Frequent arousal from hibernation linked to severity of infection and mortality in bats with white-nose syndrome

Abstract: White-nose syndrome (WNS), an emerging infectious disease that has killed over 5.5 million hibernating bats, is named for the causative agent, a white fungus (Geomyces destructans (Gd)) that invades the skin of torpid bats. During hibernation, arousals to warm (euthermic) body temperatures are normal but deplete fat stores. Temperature-sensitive dataloggers were attached to the backs of 504 free-ranging little brown bats (Myotis lucifugus) in hibernacula located throughout the northeastern USA. Dataloggers were retrieved at the end of the hibernation season and complete profiles of skin temperature data were available from 83 bats, which were categorized as: (1) unaffected, (2) WNS-affected but alive at time of datalogger removal, or (3) WNS-affected but found dead at time of datalogger removal. Histological confirmation of WNS severity (as indexed by degree of fungal infection) as well as confirmation of presence/absence of DNA from Gd by PCR was determined for 26 animals. We demonstrated that WNS-affected bats aroused to euthermic body temperatures more frequently than unaffected bats, likely contributing to subsequent mortality. Within the subset of WNS-affected bats that were found dead at the time of datalogger removal, the number of arousal bouts since datalogger attachment significantly predicted date of death. Additionally, the severity of cutaneous Gd infection correlated with the number of arousal episodes from torpor during hibernation. Thus, increased frequency of arousal from torpor likely contributes to WNS-associated mortality, but the question of how Gd infection induces increased arousals remains unanswered.

Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation

Abstract: The RefSeq project at the National Center for Biotechnology Information (NCBI) maintains and curates a publicly available database of annotated genomic, transcript, and protein sequence records (http://www.ncbi.nlm.nih.gov/refseq/). The RefSeq project leverages the data submitted to the International Nucleotide Sequence Database Collaboration (INSDC) against a combination of computation, manual curation, and collaboration to produce a standard set of stable, non-redundant reference sequences. The RefSeq project augments these reference sequences with current knowledge including publications, functional features and informative nomenclature. The database currently represents sequences from more than 55,000 organisms (>4800 viruses, >40,000 prokaryotes and >10,000 eukaryotes; RefSeq release 71), ranging from a single record to complete genomes. This paper summarizes the current status of the viral, prokaryotic, and eukaryotic branches of the RefSeq project, reports on improvements to data access and details efforts to further expand the taxonomic representation of the collection. We also highlight diverse functional curation initiatives that support multiple uses of RefSeq data including taxonomic validation, genome annotation, comparative genomics, and clinical testing. We summarize our approach to utilizing available RNA-Seq and other data types in our manual curation process for vertebrate, plant, and other species, and describe a new direction for prokaryotic genomes and protein name management.

Guidelines of the american society of mammalogists for the use of wild mammals in research

Abstract: General guidelines for use of wild mammal species are updated from the 1998 version approved by the American Society of Mammalogists (ASM) and expanded to include additional resources. Included are details on marking, housing, trapping, and collecting mammals. These guidelines cover current professional techniques and regulations involving mammals used in research. Institutional animal care and use committees, regulatory agencies, and investigators should review and approve procedures concerning use of vertebrates at any particular institution. These guidelines were prepared and approved by the ASM, whose collective expertise provides a broad and comprehensive understanding of the biology of nondomesticated mammals in their natural environments.

Emerging fungal threats to animal, plant and ecosystem health.

Abstract: The past two decades have seen an increasing number of virulent infectious diseases in natural populations and managed landscapes. In both animals and plants, an unprecedented number of fungal and fungal-like diseases have recently caused some of the most severe die-offs and extinctions ever witnessed in wild species, and are jeopardizing food security. Human activity is intensifying fungal disease dispersal by modifying natural environments and thus creating new opportunities for evolution. We argue that nascent fungal infections will cause increasing attrition of biodiversity, with wider implications for human and ecosystem health, unless steps are taken to tighten biosecurity worldwide.

The delayed rise of present-day mammals

Abstract: Did the end-Cretaceous mass extinction event, by eliminating non-avian dinosaurs and most of the existing fauna, trigger the evolutionary radiation of present-day mammals? Here we construct, date and analyse a species-level phylogeny of nearly all extant Mammalia to bring a new perspective to this question. Our analyses of how extant lineages accumulated through time show that net per-lineage diversification rates barely changed across the Cretaceous/Tertiary boundary. Instead, these rates spiked significantly with the origins of the currently recognized placental superorders and orders approximately 93 million years ago, before falling and remaining low until accelerating again throughout the Eocene and Oligocene epochs. Our results show that the phylogenetic 'fuses' leading to the explosion of extant placental orders are not only very much longer than suspected previously, but also challenge the hypothesis that the end-Cretaceous mass extinction event had a major, direct influence on the diversification of today's mammals.

2016 Guidelines of the American Society of Mammalogists for the use of wild mammals in research and education.

Abstract: Guidelines for use of wild mammal species in research are updated from [Sikes et al. (2011)][1]. These guidelines cover current professional techniques and regulations involving the use of mammals in research and teaching; they also incorporate new resources, procedural summaries, and reporting requirements. Included are details on capturing, marking, housing, and humanely killing wild mammals. It is recommended that Institutional Animal Care and Use Committees (IACUCs), regulatory agencies, and investigators use these guidelines as a resource for protocols involving wild mammals, whether studied in the field or in captivity. These guidelines were prepared and approved by the American Society of Mammalogists (ASM), in consultation with professional veterinarians experienced in wildlife research and IACUCs, whose collective expertise provides a broad and comprehensive understanding of the biology of nondomesticated mammals. The current version of these guidelines and any subsequent modifications are available online on the Animal Care and Use Committee page of the ASM website ( ). Additional resources pertaining to the use of wild animals in research are available at: . Resumen Los lineamientos para el uso de especies de mamiferos de vida silvestre en la investigacion con base en [Sikes et al. (2011)][1] se actualizaron. Dichos lineamientos cubren tecnicas y regulaciones profesionales actuales que involucran el uso de mamiferos en la investigacion y ensenanza; tambien incorporan recursos nuevos, resumenes de procedimientos y requisitos para reportes. Se incluyen detalles acerca de captura, marcaje, manutencion en cautiverio y eutanasia de mamiferos de vida silvestre. Se recomienda que los comites institucionales de uso y cuidado animal (cifras en ingles: IACUCs), las agencias reguladoras y los investigadores se adhieran a dichos lineamientos como fuente base de protocolos que involucren mamiferos de vida silvestre, ya sea investigaciones de campo o en cautiverio. Dichos lineamientos fueron preparados y aprobados por la ASM, en consulta con profesionales veterinarios experimentados en investigaciones de vida silvestre y IACUCS, de quienes cuya experiencia colectiva provee un entendimiento amplio y exhaustivo de la biologia de mamiferos no-domesticados. La presente version de los lineamientos y modificaciones posteriores estan disponibles en linea en la pagina web de la ASM, bajo Cuidado Animal y Comite de Uso: ( ). Recursos adicionales relacionados con el uso de animales de vida silvestre para la investigacion se encuentran disponibles en ( ). [1]: #ref-69