D
Dejana Mokranjac
Researcher at Ludwig Maximilian University of Munich
Publications - 56
Citations - 4653
Dejana Mokranjac is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Translocase of the inner membrane & Mitochondrion. The author has an hindex of 33, co-authored 54 publications receiving 4283 citations. Previous affiliations of Dejana Mokranjac include Protein Sciences.
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Journal ArticleDOI
Systematic screen for human disease genes in yeast
Lars M. Steinmetz,Curt Scharfe,Adam M. Deutschbauer,Dejana Mokranjac,Zelek S. Herman,Ted Jones,Angela M. Chu,Guri Giaever,Holger Prokisch,Peter J. Oefner,Ronald W. Davis +10 more
TL;DR: A systematic functional screen is applied using the pre-existing whole-genome pool of yeast deletion mutants to identify mitochondrial proteins, giving higher selection than other systematic approaches, including fivefold greater selection than gene expression analysis.
Journal ArticleDOI
Protein import into mitochondria.
Dejana Mokranjac,Walter Neupert +1 more
TL;DR: The TIM23 complex is a major translocase in the inner mitochondrial membrane that uses two energy sources, namely membrane potential and ATP, to facilitate preprotein translocation across the inner membrane and insertion into the inner membranes.
Journal ArticleDOI
The mitochondrial contact site complex, a determinant of mitochondrial architecture
Max Harner,Max Harner,Christian Körner,Christian Körner,Dirk M. Walther,Dejana Mokranjac,Johannes Kaesmacher,Johannes Kaesmacher,Ulrich Welsch,Janice Griffith,Matthias Mann,Fulvio Reggiori,Walter Neupert,Walter Neupert +13 more
TL;DR: Using quantitative high‐resolution mass spectrometry, a novel complex is identified, the mitochondrial contact site (MICOS) complex, formed by a set of mitochondrial membrane proteins that is essential for the formation of CS.
Journal ArticleDOI
Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria
TL;DR: A model in which Tim14 is required for the activation of mtHsp70 and enables this chaperone to act in a rapid and regulated manner in the Tim44‐mediated trapping of unfolded preproteins entering the matrix is proposed.
Journal ArticleDOI
Tim50, a novel component of the TIM23 preprotein translocase of mitochondria
Dejana Mokranjac,Stefan A. Paschen,Christian Kozany,Holger Prokisch,Suzanne Hoppins,Frank E. Nargang,Walter Neupert,Kai Hell +7 more
TL;DR: It is suggested that Tim50 plays a crucial role in the transfer of preproteins from the TOM complex to the TIM23 complex through the intermembrane space.