D
Denise A. Meagher
Researcher at Rockefeller University
Publications - 2
Citations - 1215
Denise A. Meagher is an academic researcher from Rockefeller University. The author has contributed to research in topics: Bottom-up proteomics & Top-down proteomics. The author has an hindex of 2, co-authored 2 publications receiving 1188 citations.
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Mass spectrometric identification of proteins from silver‐stained polyacrylamide gel: A method for the removal of silver ions to enhance sensitivity
TL;DR: By using the destaining method, the sensitivity and quality of mass spectra is increased for matrix‐assisted laser desorption ionization‐time of flight (MALDI‐TOF) mass spectrometric analysis, permitting more proteins to be identified by peptide mass database analysis.
Journal ArticleDOI
Composition and Functional Characterization of Yeast 66S Ribosome Assembly Intermediates
Piyanun Harnpicharnchai,Jelena Jakovljevic,Edward W. Horsey,Tiffany D. Miles,Judibelle Roman,Michael P. Rout,Denise A. Meagher,Brian S. Imai,Yurong Guo,Cynthia J. Brame,Jeffrey Shabanowitz,Donald F. Hunt,John L. Woolford +12 more
TL;DR: This work affinity purified yeast preribosomal particles containing the nucleolar protein Nop7p and developed means to separate their components, demonstrating that proteomic approaches in concert with genetic tools provide powerful means to purify and characterize ribosome assembly intermediates.