D
Deqin Sun
Researcher at Brigham and Women's Hospital
Publications - 18
Citations - 3795
Deqin Sun is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Squamous intraepithelial lesion & Epidermoid carcinoma. The author has an hindex of 18, co-authored 18 publications receiving 3647 citations. Previous affiliations of Deqin Sun include Chulalongkorn University.
Papers
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Journal ArticleDOI
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
Annie Yang,Ronen Schweitzer,Deqin Sun,Mourad Kaghad,Nancy Walker,Roderick T. Bronson,Clifford J. Tabin,Arlene H. Sharpe,Daniel Caput,Christopher P. Crum,Frank McKeon +10 more
TL;DR: It is reported that mice homozygous for a disrupted p63 gene have major defects in their limb, craniofacial and epithelial development, and results indicate that p63 is critical for maintaining the progenitor-cell populations that are necessary to sustain epithelialDevelopment and morphogenesis.
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Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia.
Jeffrey T. Keating,Aida Cviko,Sabine Riethdorf,Lutz Riethdorf,Bradley J. Quade,Deqin Sun,Stefan Duensing,Ellen E. Sheets,Karl Münger,Christopher P. Crum +9 more
TL;DR: Ki-67, cyclin E, and p16 are complementary surrogate biomarkers for HPV-related preinvasive squamous cervical disease and use of these biomarkers in combination for resolving diagnostic problems, with an appreciation of potential background staining, is recommended.
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h-Caldesmon expression effectively distinguishes endometrial stromal tumors from uterine smooth muscle tumors.
Marisa R. Nucci,Jerome T. O'connell,Phyllis C. Huettner,Aida Cviko,Deqin Sun,Bradley J. Quade +5 more
TL;DR: H-caldesmon appears to be a more sensitive and specific marker of smooth muscle differentiation in the uterus than desmin and may be a useful tool for distinguishing and classifying uterine mesenchymal tumors.
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Histologic and immunophenotypic classification of cervical carcinomas by expression of the p53 homologue p63: a study of 250 cases.
Tao-Yeuan Wang,Be-Fong Chen,Yuh-Cheng Yang,Hao Chen,Yunmei Wang,Aida Cviko,Bradley J. Quade,Deqin Sun,Annie Yang,Frank McKeon,Christopher P. Crum +10 more
TL;DR: This study correlated p63 expression with morphologic phenotype and human papillomavirus type in a wide range of cervical neoplasms to identify a strong association between HPV 16 and p63 positivity and clarify the spectrum of poorly differentiated carcinomas lacking either squamous or neuroendocrine differentiation.
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Expression of the p53 Homologue p63 in Early Cervical Neoplasia
Bradley J. Quade,Annie Yang,Yunmei Wang,Deqin Sun,Jeong-Ja Park,Ellen E. Sheets,Aida Cviko,J.M. Federschneider,Roxana Peters,Frank McKeon,Christopher P. Crum +10 more
TL;DR: The broader range of p63 expression relevant to keratin 14 and bcl-2 indicates that p63 may identify additional subsets of benign and neoplastic epithelial basal cells in the cervical transformation zone and may be useful in studying cell differentiation in the early stages of neoplastics change in this region.