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Detlef Günther

Researcher at ETH Zurich

Publications -  438
Citations -  35958

Detlef Günther is an academic researcher from ETH Zurich. The author has contributed to research in topics: Laser ablation & Inductively coupled plasma mass spectrometry. The author has an hindex of 83, co-authored 428 publications receiving 31702 citations. Previous affiliations of Detlef Günther include Max Planck Society & École Polytechnique Fédérale de Lausanne.

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In situ analysis of major and trace elements of anhydrous minerals by LA-ICP-MS without applying an internal standard

TL;DR: In this paper, an internal standard-independent calibration strategy for LA-ICP-MS analysis of anhydrous minerals and glasses was described, where the ablation yield correction factor (AYCF) was used to correct the matrix-dependent absolute amount of materials ablated during each run.
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Inter-laboratory note. Laser ablation inductively coupled plasma mass spectrometric transient signal data acquisition and analyte concentration calculation

TL;DR: In this paper, the authors discuss data acquisition and reduction considerations in LA-ICP-MS analysis and suggest optimum data acquisition parameters for time-resolved data acquisition, sensitivity calibration is obtained from reference materials with known analyte concentrations and naturally occurring internal standards are used to correct for the multiplicative correction factors.
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Determination of Reference Values for NIST SRM 610–617 Glasses Following ISO Guidelines

TL;DR: In this article, the authors presented new reference values for the NIST SRM 610-617 glasses following ISO guidelines and the International Association of Geoanalysts' protocol, and determined quantitatively possible element inhomogeneities using different test portion masses of 1, 0.1 and 0.02μg.
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Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

TL;DR: The coupled immunohistochemical and immunocytochemical methods with high-resolution laser ablation to CyTOF mass cytometry enables the simultaneous imaging of 32 proteins and protein modifications at subcellular resolution and complements existing imaging approaches.
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Accurate U-Pb Age and Trace Element Determinations of Zircon by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry

TL;DR: In this paper, laser ablation-inductively coupled plasma-mass spectrometry was used for age determination of zircons of Proterozoic to Oligocene ages (1060-31 Ma).