D
Detlef Günther
Researcher at ETH Zurich
Publications - 438
Citations - 35958
Detlef Günther is an academic researcher from ETH Zurich. The author has contributed to research in topics: Laser ablation & Inductively coupled plasma mass spectrometry. The author has an hindex of 83, co-authored 428 publications receiving 31702 citations. Previous affiliations of Detlef Günther include Max Planck Society & École Polytechnique Fédérale de Lausanne.
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In situ analysis of major and trace elements of anhydrous minerals by LA-ICP-MS without applying an internal standard
TL;DR: In this paper, an internal standard-independent calibration strategy for LA-ICP-MS analysis of anhydrous minerals and glasses was described, where the ablation yield correction factor (AYCF) was used to correct the matrix-dependent absolute amount of materials ablated during each run.
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Inter-laboratory note. Laser ablation inductively coupled plasma mass spectrometric transient signal data acquisition and analyte concentration calculation
TL;DR: In this paper, the authors discuss data acquisition and reduction considerations in LA-ICP-MS analysis and suggest optimum data acquisition parameters for time-resolved data acquisition, sensitivity calibration is obtained from reference materials with known analyte concentrations and naturally occurring internal standards are used to correct for the multiplicative correction factors.
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Determination of Reference Values for NIST SRM 610–617 Glasses Following ISO Guidelines
Klaus Peter Jochum,Ulrike Weis,Brigitte Stoll,D. V. Kuzmin,Qichao Yang,Ingrid Raczek,Dorrit E. Jacob,Andreas Stracke,Karin Birbaum,Daniel A. Frick,Detlef Günther,Jacinta Enzweiler +11 more
TL;DR: In this article, the authors presented new reference values for the NIST SRM 610-617 glasses following ISO guidelines and the International Association of Geoanalysts' protocol, and determined quantitatively possible element inhomogeneities using different test portion masses of 1, 0.1 and 0.02μg.
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Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry
Charlotte Giesen,Hao A. O. Wang,Denis Schapiro,Nevena Zivanovic,Andrea Jacobs,Bodo Hattendorf,Peter J. Schüffler,Daniel Grolimund,Joachim M. Buhmann,Simone Brandt,Zsuzsanna Varga,Peter J. Wild,Detlef Günther,Bernd Bodenmiller +13 more
TL;DR: The coupled immunohistochemical and immunocytochemical methods with high-resolution laser ablation to CyTOF mass cytometry enables the simultaneous imaging of 32 proteins and protein modifications at subcellular resolution and complements existing imaging approaches.
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Accurate U-Pb Age and Trace Element Determinations of Zircon by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry
Honglin Yuan,Honglin Yuan,Shan Gao,Shan Gao,Xiaoming Liu,Huiming Li,Detlef Günther,Fu-Yuan Wu +7 more
TL;DR: In this paper, laser ablation-inductively coupled plasma-mass spectrometry was used for age determination of zircons of Proterozoic to Oligocene ages (1060-31 Ma).