D
Dhananjay Gupta
Researcher at University of Vermont
Publications - 30
Citations - 1266
Dhananjay Gupta is an academic researcher from University of Vermont. The author has contributed to research in topics: Insulin & Islet. The author has an hindex of 16, co-authored 29 publications receiving 1155 citations. Previous affiliations of Dhananjay Gupta include University of Saskatchewan & Indiana University.
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Trigonellafoenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reversing the altered glycolytic, gluconeogenic and lipogenic enzymes.
TL;DR: The therapeutic role of Trigonella seed powder in type1 diabetes as exemplified in this study can be attributed to the change of glucose and lipid metabolising enzyme activities to normal values, thus stabilizing glucose homeostasis in the liver and kidney.
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Regulation of metabolic pathways in liver and kidney during experimental diabetes: Effects of antidiabetic compounds.
TL;DR: Almost complete reversal of the metabolic changes has been achieved in the activities of key enzymes of metabolic pathways in liver and kidney and an effective glucose control has been achieve suggesting a combination of therapies in the treatment of metabolic disturbance of the diabetic state.
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Change in the lipid profile, lipogenic and related enzymes in the livers of experimental diabetic rats: effect of insulin and vanadate
TL;DR: Results indicate that vanadate administration to diabetic animals normalizes blood glucose and causes marked improvement of altered lipid metabolism during diabetes, and suggest the possible use of vanadates as insulin replacement in the therapy of diabetes when administered at pharmacological doses.
Journal Article
Modulation of some gluconeogenic enzyme activities in diabetic rat liver and kidney: effect of antidiabetic compounds.
TL;DR: The significantly increased activities of the two enzymes during diabetes in liver and kidney were found to be lowered to almost control values by the use of the antidiabetic compounds.
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The role of peroxisome proliferator-activated receptor γ in pancreatic β cell function and survival: therapeutic implications for the treatment of type 2 diabetes mellitus.
TL;DR: The mechanisms by which PPAR‐γ activation acts to maintain β cell function and survival in type 2 diabetes mellitus are reviewed and some of the current controversies in this field are highlighted.