D
Dia-Eldin A. Elnaiem
Researcher at University of Maryland Eastern Shore
Publications - 23
Citations - 1114
Dia-Eldin A. Elnaiem is an academic researcher from University of Maryland Eastern Shore. The author has contributed to research in topics: Leishmania major & Leishmania. The author has an hindex of 16, co-authored 22 publications receiving 995 citations. Previous affiliations of Dia-Eldin A. Elnaiem include National Institutes of Health.
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Journal ArticleDOI
Immunity to a salivary protein of a sand fly vector protects against the fatal outcome of visceral leishmaniasis in a hamster model.
Regis Gomes,Regis Gomes,Clarissa Teixeira,Clarissa Teixeira,Maria Jânia Teixeira,Fabiano Oliveira,Fabiano Oliveira,Maria José Menezes,Claire Crola da Silva,Camila I. de Oliveira,José Carlos Miranda,Dia-Eldin A. Elnaiem,Shaden Kamhawi,Jesus G. Valenzuela,Cláudia Brodskyn +14 more
TL;DR: It is shown that immunity to a defined salivary protein (LJM19) confers powerful protection against the fatal outcome of a parasitic disease, which reinforces the concept of using components of arthropod saliva in vaccine strategies against vector-borne diseases.
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The midgut transcriptome of Lutzomyia longipalpis: comparative analysis of cDNA libraries from sugar-fed, blood-fed, post-digested and Leishmania infantum chagasi-infected sand flies
Ryan C. Jochim,Ryan C. Jochim,Clarissa Teixeira,Andre Laughinghouse,Jianbing Mu,Fabiano Oliveira,Regis Gomes,Dia-Eldin A. Elnaiem,Jesus G. Valenzuela +8 more
TL;DR: This analysis suggests that Leishmania infantum chagasi alters the expression profile of certain midgut transcripts in the sand fly during blood meal digestion and that this modulation may be relevant for the survival and establishment of the parasite in the gut of the fly.
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Discovery of markers of exposure specific to bites of Lutzomyia longipalpis, the vector of Leishmania infantum chagasi in Latin America.
Clarissa Teixeira,Regis Gomes,Nicolas Collin,David Reynoso,Ryan C. Jochim,Fabiano Oliveira,Amy E. Seitz,Dia-Eldin A. Elnaiem,Arlene de Jesus Mendes Caldas,Ana Paula de Souza,Cláudia Brodskyn,Ivete Lopes de Mendonça,Carlos Henrique Nery Costa,Petr Volf,Aldina Barral,Shaden Kamhawi,Jesus G. Valenzuela +16 more
TL;DR: Salivary recombinant proteins are of value as markers of vector exposure in humans and of sand fly exposure in dogs.
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Ecology and Control of the Sand Fly Vectors of Leishmania donovani in East Africa, with Special Emphasis on Phlebotomus orientalis
TL;DR: A literature review is provided on the state of knowledge of the ecology and control of the sand fly vectors of Leishmania donovani in East Africa, with a special emphasis on Phlebotomus orientalis, foundings on sand fly fauna and other circumstantial evidence indicate that P. martini is also responsible for transmission of L.Donovani.
Journal ArticleDOI
The Mating Competence of Geographically Diverse Leishmania major Strains in Their Natural and Unnatural Sand Fly Vectors
Ehud Inbar,Natalia S. Akopyants,Mélanie Charmoy,Audrey Romano,Phillip G. Lawyer,Dia-Eldin A. Elnaiem,Florence Kauffmann,Mourad Barhoumi,Michael E. Grigg,Katherine Owens,Michael P. Fay,Deborah E. Dobson,Jahangheer S. Shaik,Stephen M. Beverley,David B. Sacks +14 more
TL;DR: Comparisons of the timing of hybrid formation with the presence of developmental stages suggest nectomonads as the most likely sexually competent stage, with hybrids emerging well before the first appearance of metacyclic promastigotes.