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Diane V. Havlir
Researcher at University of California, San Francisco
Publications - 462
Citations - 41540
Diane V. Havlir is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 76, co-authored 422 publications receiving 37607 citations. Previous affiliations of Diane V. Havlir include Case Western Reserve University & Harvard University.
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Journal ArticleDOI
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
Myron S. Cohen,Ying Q. Chen,Marybeth McCauley,Theresa Gamble,Mina C. Hosseinipour,Nagalingeswaran Kumarasamy,James Hakim,Johnstone Kumwenda,Beatriz Grinsztejn,José Henrique Pilotto,Sheela Godbole,Sanjay Mehendale,Suwat Chariyalertsak,Breno Santos,Kenneth H. Mayer,Irving F. Hoffman,Susan H. Eshleman,Estelle Piwowar-Manning,Lei Wang,Joseph Makhema,Lisa A. Mills,Guy de Bruyn,Ian Sanne,Joseph J. Eron,Joel E. Gallant,Diane V. Havlir,Susan Swindells,Heather J. Ribaudo,Vanessa Elharrar,David N. Burns,Taha E. Taha,Karin Nielsen-Saines,David D. Celentano,Myron Essex,Thomas R. Fleming +34 more
TL;DR: In this article, Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples.
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Recovery of replication-competent HIV despite prolonged suppression of plasma viremia.
Joseph K. Wong,Marjan Hezareh,Huldrych F. Günthard,Diane V. Havlir,Caroline Ignacio,Celsa A. Spina,Douglas D. Richman +6 more
TL;DR: In this article, the authors showed that activation of patient CD4 lymphocytes with immobilized antibodies to CD3 and CD28 enabled the isolation of virus from six patients despite the suppression of their plasma HIV RNA to fewer than 50 copies per milliliter for up to 2 years.
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Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior Antiretroviral Therapy
Roy M. Gulick,John W. Mellors,Diane V. Havlir,Joseph J. Eron,Charles J. Gonzalez,Deborah McMahon,Douglas D. Richman,Fred T. Valentine,Leslie Jonas,Anne R. Meibohm,Emilio A. Emini,Chodakewitz Jeffrey A +11 more
TL;DR: In most HIV-infected patients with prior antiretroviral therapy, the combination of indinavir, zidovudine, and lamivudine reduces levels of HIV RNA to less than 500 copies per milliliter for as long as one year.
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Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.
Victor Appay,P. Rod Dunbar,Margaret F. C. Callan,Paul Klenerman,Geraldine M. Gillespie,Laura Papagno,Graham S. Ogg,Abigail S. King,Franziska Lechner,Celsa A. Spina,Susan J. Little,Diane V. Havlir,Douglas D. Richman,Norbert H. Gruener,Gerd R. Pape,Anele Waters,Philippa Easterbrook,Mariolina Salio,Vincenzo Cerundolo,Andrew J. McMichael,Sarah Rowland-Jones +20 more
TL;DR: There are significant enrichments at different stages of cellular differentiation in the chronic phase of persistent infection according to the viral specificity, which suggests that distinct memory T-cell populations are established in different virus infections.
Journal ArticleDOI
The end of AIDS: HIV infection as a chronic disease
TL;DR: Concerns are growing that the multimorbidity associated with HIV disease could affect healthy ageing and overwhelm some health-care systems, particularly those in resource-limited regions that have yet to develop a chronic care model fully.