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Diederick E. Grobbee

Researcher at Utrecht University

Publications -  1108
Citations -  136069

Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.

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Vasomotor symptoms are associated with a lower bone mineral density.

TL;DR: The findings show that vasomotor symptoms are associated with reduced bone density, and it could be hypothesized that women with vasom motor symptoms might be more susceptible to the beneficial effects of estrogens, possibly by neutralizing the effect of estrogen fluctuations.
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Menstruation during and after caloric restriction : The 1944-1945 dutch famine

TL;DR: Famine relates to concurrent menstrual irregularity, and exposure in childhood seems to affect the subsequent menstrual pattern.
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Antipsychotic drugs may worsen metabolic control in type 2 diabetes mellitus.

TL;DR: It seems that use of antipsychotics by patients with type 2 diabetes mellitus is associated with initiation of insulin therapy (i.e., "secondary failure"), especially in the first 2 years of the disease.
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Best reproducibility of the ankle-arm index was calculated using Doppler and dividing highest ankle pressure by highest arm pressure

TL;DR: To achieve the best reproducibility and smallest systematic difference in the AAI, single SBP measurements should be obtained by Doppler in the brachial artery, posterior tibial artery and dorsalis pedis artery.
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Cumulative genetic defects in carcinogen metabolism may increase breast cancer risk (The Netherlands).

TL;DR: The results of this study suggest that presence of three or more putative at risk genotypes increases breast cancer risk.