D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Noninvasive arterial measurements of vascular damage in healthy young adults: relation to coronary heart disease risk.
Marijke J.C.A. van Trijp,Cuno S.P.M. Uiterwaal,Willem Jan W. Bos,Anath Oren,Diederick E. Grobbee,Michiel L. Bots +5 more
TL;DR: In young men, PWV and CIMT are better measures of CHD risk than AIx; in women, AIx, PWv and CimT estimate CHDrisk equally well.
Journal ArticleDOI
Plasma annexin A5 level relates inversely to the severity of coronary stenosis
Lambertus J.H. van Tits,Waander L. van Heerde,Gerly M. van der Vleuten,Jacqueline de Graaf,Diederick E. Grobbee,Lucy P.L. van de Vijver,Anton F. H. Stalenhoef,Hans M.G. Princen +7 more
TL;DR: TheOxLDL/annexin A5 ratio is a better marker of the severity of coronary stenosis than oxLDL alone, may reflect the presence and extent of the atherosclerotic cardiovascular disease, and might prove useful for preclinical screening purposes.
Journal ArticleDOI
Poor health-related quality of life of patients with indication for chronic cardiac pacemaker therapy.
J.W. Martijn van Eck,Norbert M. van Hemel,Johannes C. Kelder,Arjan van den Bos,William Taks,Diederick E. Grobbee,Karel G.M. Moons +6 more
TL;DR: This study systematically assessed the HRQoL in a large unselected cohort of patients with a conventional indication for PM therapy, and found no significant difference in quality of life between the two groups.
Journal ArticleDOI
Classical Cardiovascular Risk Factors and HIV are Associated With Carotid Intima-Media Thickness in Adults From Sub-Saharan Africa: Findings From H3Africa AWI-Gen Study.
Engelbert A. Nonterah,Palwende R. Boua,Kerstin Klipstein-Grobusch,Kerstin Klipstein-Grobusch,Gershim Asiki,Lisa K. Micklesfield,Godfred Agongo,Stuart A. Ali,Felistas Mashinya,H. Sorgho,Seydou Nakanabo-Diallo,Cornelius Debpuur,Catherine Kyobutungi,Marianne Alberts,Shane A. Norris,Stephen Tollman,Halidou Tinto,Cassandra Soo,Freedom Mukomana,Scott Hazelhurst,Alisha N. Wade,Kathleen Kahn,Abraham Oduro,Diederick E. Grobbee,Osman Sankoh,Michèle Ramsay,Michiel L. Bots,Nigel J. Crowther,as members +28 more
TL;DR: Given the rising prevalence of cardiovascular diseases risk factors in sub‐Saharan Africa, atherosclerotic diseases may become a major pan‐African epidemic unless preventive measures are taken particularly for prevention of hypertension, obesity, and smoking.
Journal ArticleDOI
A post-hoc analysis of serotype-specific vaccine efficacy of 13-valent pneumococcal conjugate vaccine against clinical community acquired pneumonia from a randomized clinical trial in the Netherlands
Bradford D Gessner,Qin Jiang,Cornelis H. van Werkhoven,Heather L Sings,Chris Webber,Daniel A. Scott,William C. Gruber,Diederick E. Grobbee,Marc J. M. Bonten,Luis Jodar +9 more
TL;DR: Serotype-specific vaccine efficacy (VE) against adult community acquired pneumonia (CAP) remains poorly defined, yet such data are important for assessing the utility of adult pneumococcal conjugate vaccine (PCV) programs.