D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
The impact of 13-valent pneumococcal conjugate vaccination on virus-associated community-acquired pneumonia in elderly: Exploratory analysis of the CAPiTA trial
Susanne M. Huijts,F.E.J. Coenjaerts,Marieke Bolkenbaas,C.H. van Werkhoven,Diederick E. Grobbee,M. J. M. Bonten +5 more
TL;DR: In a randomized study of 84 496 elderly individuals with a high uptake of influenza vaccination, PCV13 was not associated with a statistically significant reduction of influenza or virus-associated CAP.
Journal ArticleDOI
Completeness of carotid intima media thickness measurements depends on body composition: the RADIANCE 1 and 2 trials.
Soner Dogan,Raphaël Duivenvoorden,Diederick E. Grobbee,John J.P. Kastelein,Charles L. Shear,Gregory W. Evans,Frank L.J. Visseren,Michiel L. Bots +7 more
TL;DR: With the current ultrasound protocols it is possible to obtain a very high level of completeness in CIMT measurements and its relation with vascular risk factors, and segment-specific data indicated that in FH patients, completeness was less for the near wall of the left and right internal carotid artery as compared to other segments.
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RCTs and observational studies to determine the effect of prophylaxis in severe haemophilia.
TL;DR: It has been suggested that more RCTs should be conducted in the evaluation of haemophilia treatment, including prophylaxis, because special efforts should be made to achieve comparability of prognosis, that is, to avoid ‘confounding by indication’.
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The angiotensinogen gene M235T polymorphism and development of preeclampsia/eclampsia: a meta-analysis and meta-regression of observational studies.
TL;DR: A meta-analysis expands the findings on hypertension by showing that the presence of the T allele of the angiotensinogen gene is associated with an increased risk to develop preeclampsia/eClampsia.
Journal ArticleDOI
Alcohol and arterial wave reflections in middle aged and elderly men.
M. J. C. A. van Trijp,Willem Jan W. Bos,Y. T. van der Schouw,Majon Muller,Diederick E. Grobbee,Michiel L. Bots +5 more
TL;DR: This study investigates the relation of alcohol consumption with AIx in a population‐based cohort of men aged 40–80 years and finds a U‐shaped relationship with a protective effect of moderate alcohol consumption.