D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Exhaled nitric oxide in 4-year-old children: relationship with asthma and atopy
J. E. Brussee,Henriette A. Smit,Marjan Kerkhof,Laurens P. Koopman,A. H. Wijga,D. S. Postma,Jorrit Gerritsen,Diederick E. Grobbee,Bert Brunekreef,J. C. De Jongste +9 more
TL;DR: This study is one of the few large-scale epidemiological studies among 4-yr-old children from the general population showing that children with symptoms of asthma and atopy have higher levels of exhaled nitric oxide than those without.
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Sex differences in risk factor management of coronary heart disease across three regions.
Min Zhao,Ilonca Vaartjes,Ian D. Graham,Diederick E. Grobbee,Wilko Spiering,Kerstin Klipstein-Grobusch,Kerstin Klipstein-Grobusch,Mark Woodward,Sanne A.E. Peters +8 more
TL;DR: Risk factor management for the secondary prevention of CHD was generally worse in women than in men, and the magnitude and direction of the sex differences varied by region.
Journal ArticleDOI
Combined effect of alcohol consumption and lifestyle behaviors on risk of type 2 diabetes
Michel M. Joosten,Michel M. Joosten,Diederick E. Grobbee,Daphne L. van der A,W. M. Monique Verschuren,Henk F. J. Hendriks,Joline W.J. Beulens +6 more
TL;DR: In subjects already at lower risk of type 2 diabetes on the basis of multiple low-risk lifestyle behaviors, moderate alcohol consumption was associated with an approximately 40% lower risk compared with abstention.
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Plasminogen Activator Inhibitor 4G Polymorphism Is Associated With Decreased Risk of Cerebrovascular Mortality in Older Women
Mark Roest,Yvonne T. van der Schouw,Jan Dirk Banga,Mariëlle J. Tempelman,Philip G. de Groot,Jan J. Sixma,Diederick E. Grobbee +6 more
TL;DR: Findings are suggestive of an important contribution of PAI-1 in cerebrovascular pathology, probably via pathways other than fibrinolysis, and may protect against destabilization of the atherosclerotic plaque or it may inhibit neurotoxicity of tissue plasminogen activator in the brain.
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Pro-Inflammatory Markers in Relation to Cardiovascular Disease in HIV Infection. A Systematic Review
Alinda G. Vos,Nikmah Salamia Idris,Roos E. Barth,Kerstin Klipstein-Grobusch,Diederick E. Grobbee +4 more
TL;DR: A relation between some inflammatory markers and CVD, however, no consistent relation is observed for CIMT, and further research should focus on prospective studies and a selected set of inflammatory markers.