D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
No relationship between circulating levels of sex steroids and mammographic breast density: the Prospect-EPIC cohort
Martijn Verheus,Petra H.M. Peeters,Paulus A.H. van Noord,Yvonne T. van der Schouw,Diederick E. Grobbee,Carla H. van Gils +5 more
TL;DR: The hypothesis that sex steroids increase postmenopausal breast cancer risk via an increase in breast density is supported, but both oestrogens and testosterone were inversely related with percent breast density, but these relationships disappeared after adjustment for BMI.
Journal ArticleDOI
High prevalence of secondary hypertension and insulin resistance in patients with refractory hypertension.
N. Martell,Matilde Rodríguez-Cerrillo,Diederick E. Grobbee,M. Dolores López-Eady,Carmen Fernandez-Pinilla,M. Avila,Arturo Fernández-Cruz,M. Luque +7 more
TL;DR: Findings show that among normokaliemic treatment-resistant hypertension, the presence of hyperaldosteronism and pheochromocitoma is quite high, and treatment resistance in hypertensive patients appears to be associated with insulin resistance.
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Influence of estrogen receptor alpha and progesterone receptor polymorphisms on the effects of hormone therapy on mammographic density.
Fränzel J.B. Van Duijnhoven,Petra H.M. Peeters,Ruth Warren,Sheila Bingham,André G. Uitterlinden,Paulus A.H. van Noord,Evelyn M. Monninkhof,Diederick E. Grobbee,Carla H. van Gils +8 more
TL;DR: It is suggested that specific polymorphisms in the ESR1 and PGR genes may make women more susceptible to the effects of hormone therapy use on mammographic density.
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The Octopus Study: Rationale and Design of Two Randomized Trials on Medical Effectiveness, Safety, and Cost-Effectiveness of Bypass Surgery on the Beating Heart
Diederik van Dijk,Arno P. Nierich,Frank D. Eefting,Erik Buskens,Hendrik M. Nathoe,Erik W.L. Jansen,Cornelius Borst,Johannes T. A. Knape,Johan J. Bredée,Etienne O. Robles de Medina,Diederick E. Grobbee,Jan C. Diephuis,Peter de Jaegere +12 more
TL;DR: The Octopus Study consists of two multicenter randomized clinical trials in which coronary artery bypass grafting on the beating heart using the Utrecht Octopus Method is compared to intracoronary stent implantation and conventional CABG.
Journal ArticleDOI
Epidemiology of abdominal aortic aneurysms.
TL;DR: The available literature on etiology, diagnosis, prevalence, incidence, risk indicators, and prognosis of AAA is reviewed to detect gaps in the knowledge and to make suggestions as to the direction of future research in the light of the question as to whether screening of the general population for aneurysms of the abdominal aorta should be advocated.