D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
The prevalence of primary open-angle glaucoma in a population-based study in The Netherlands. The Rotterdam Study.
I. Dielemans,Johannes R. Vingerling,Roger C. W. Wolfs,Albert Hofman,Diederick E. Grobbee,Paulus T. V. M. de Jong +5 more
TL;DR: The Rotterdam Study as discussed by the authors assessed the prevalence of primary open-angle glaucoma (POAG) in a defined population in the Netherlands, and the overall prevalence of POAG was 1.10% (95% confidence interval [CI]: 1.09,1.11).
Journal ArticleDOI
Early Outcome After Off-Pump Versus On-Pump Coronary Bypass Surgery Results From a Randomized Study
Diederik van Dijk,Arno P. Nierich,Erik W.L. Jansen,Hendrik M. Nathoe,Willem J.L. Suyker,Jan C. Diephuis,Wim-Jan van Boven,Cornelius Borst,Erik Buskens,Diederick E. Grobbee,Etienne O. Robles de Medina,Peter de Jaegere +11 more
TL;DR: This work has shown that the use of cardiopulmonary bypass during coronary artery bypass surgery (CABG) has been associated with substantial morbidity and the recent introduction of cardiac stabilizers facilitates this association.
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Missing covariate data in medical research: To impute is better than to ignore
Kristel J.M. Janssen,A. Rogier T. Donders,Frank E. Harrell,Yvonne Vergouwe,Qingxia Chen,Diederick E. Grobbee,Karel G.M. Moons +6 more
TL;DR: This study shows that simple methods to deal with missing data can lead to seriously misleading results, and advises to consider multiple imputation.
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Internal and external validation of predictive models: a simulation study of bias and precision in small samples.
Ewout W. Steyerberg,Sacha E. Bleeker,Henriëtte A. Moll,Diederick E. Grobbee,Karel G.M. Moons +4 more
TL;DR: Bootstrapping for internal validation gives reasonably valid estimates of the expected optimism in predictive performance provided that any selection of predictors is taken into account, and should be used for external validation.
Journal ArticleDOI
Mortality in adult congenital heart disease
Carianne L. Verheugt,Carianne L. Verheugt,Cuno S.P.M. Uiterwaal,Enno T. van der Velde,Folkert J. Meijboom,Petronella G. Pieper,Arie P.J. van Dijk,Hubert W. Vliegen,Diederick E. Grobbee,Barbara J. M. Mulder +9 more
TL;DR: Mortality risk, particularly by heart failure, is increased by virtually all complications, particularly in the young, and is equally hazardous in younger as in older patients.