Dietmar Blohm

TL;DR: A DNA microarray containing 64 functional oligonucleotide probes for the identification of 30 out of the 50 fish species investigated was developed and represents the next step towards an automated and easy-to-handle method to identify fish, ichthyoplankton, and fish products.

TL;DR: Quantitative measurements on microplates indicate that DDI proceeds with a higher immobilization efficiency than conventional immobilization techniques, such as the binding of the biotinylated proteins to streptavidin-coated surfaces or direct physisorption, and simultaneous immobilization of different compounds using microstructured oligonucleotide arrays as immobilization matrices demonstrate that D DI proceeds with site selectivity due to the unique specificity of Watson-Crick base pairing.

TL;DR: Realizing the microsphere-based massively parallel signature sequencing technique as fluid microarrays, building new types of protein arrays and constructing miniaturized flow-through systems, exemplify the intense developments that are now ongoing in this field.

TL;DR: A novel method for the surface immobilization of DNA using pre-fabricated polyamidoamine (PAMAM) starburst dendrimers as mediator moieties with a very high immobilization efficiency for amino-modified DNA-oligomers and a remarkable high stability during repeated regeneration and re-using cycles is reported.

TL;DR: In this article, the authors describe a fast and reliable technique for generating large diversities of anti-iotypic single chain antibody fragments from non-immunized phagemid libraries using phage display.