D
Dinesh C. Indurthi
Researcher at University of Sydney
Publications - 27
Citations - 895
Dinesh C. Indurthi is an academic researcher from University of Sydney. The author has contributed to research in topics: Nicotinic agonist & Agonist. The author has an hindex of 10, co-authored 22 publications receiving 784 citations. Previous affiliations of Dinesh C. Indurthi include University of Delaware & Delaware Biotechnology Institute.
Papers
More filters
Journal ArticleDOI
Clostridia: the importance of their exceptional substrate and metabolite diversity for biofuel and biorefinery applications.
TL;DR: Pathway engineering to combine established substrate-utilization programs, such as for cellulose, CO2/H2 or CO, with desirable metabolic programs could lead to modular design of strains suitable for many applications.
Journal ArticleDOI
Resolving the TCA cycle and pentose-phosphate pathway of Clostridium acetobutylicum ATCC 824: Isotopomer analysis, in vitro activities and expression analysis
Scott B. Crown,Dinesh C. Indurthi,Woo Suk Ahn,Jungik Choi,Eleftherios T. Papoutsakis,Maciek R. Antoniewicz +5 more
TL;DR: Dynamic gene expression analysis of the putative Re-CS gene (CAC0970), its operon, and all glycolysis, pentose-phosphate pathway, and TCA cycle genes identify genes and their degree of involvement in these core pathways that support the powerful primary metabolism of this industrial organism.
Journal ArticleDOI
Synthetic tolerance: three noncoding small RNAs, DsrA, ArcZ and RprA, acting supra-additively against acid stress
Stefan M. Gaida,Mohab A. Al-Hinai,Dinesh C. Indurthi,Sergios A. Nicolaou,Eleftherios T. Papoutsakis +4 more
TL;DR: It is shown that simultaneous overexpression of noncoding small RNAs, DsrA, RprA and ArcZ, which are translational RpoS activators, increased acid tolerance supra-additively up to 8500-fold during active cell growth, and provided protection against carboxylic acid and oxidative stress.
Journal ArticleDOI
Small RNAs in the Genus Clostridium
Yili Chen,Yili Chen,Dinesh C. Indurthi,Dinesh C. Indurthi,Shawn William Jones,Shawn William Jones,Shawn William Jones,Eleftherios T. Papoutsakis,Eleftherios T. Papoutsakis,Eleftherios T. Papoutsakis +9 more
TL;DR: A conserved, novel sRNA is identified which, together with the downstream gene coding for an ATP-binding cassette (ABC) transporter gene, responds to the antibiotic clindamycin.
Journal ArticleDOI
A genomic-library based discovery of a novel, possibly synthetic, acid-tolerance mechanism in Clostridium acetobutylicum involving non-coding RNAs and ribosomal RNA processing.
Jacob R. Borden,Shawn William Jones,Shawn William Jones,Dinesh C. Indurthi,Yili Chen,Eleftherios T. Papoutsakis,Eleftherios T. Papoutsakis +6 more
TL;DR: By hybridizing against unprocessed rRNA precursors, ncRNA(RD7) alters rRNA processing, and these alterations result in acid tolerance, possibly through a mechanism involving the Ffh protein.