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Division on Earth

Bio: Division on Earth is an academic researcher. The author has contributed to research in topics: Animal Care Committees & Laboratory Animal Science. The author has an hindex of 1, co-authored 1 publications receiving 13165 citations.

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01 Feb 1996

13,908 citations


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Journal ArticleDOI
TL;DR: The American Society of Mammalogists (ASM) published guidelines for the use of wild mammal species in research as mentioned in this paper, which provide a broad and comprehensive understanding of the biology of nondomesticated mammals in their natural environments.
Abstract: General guidelines for use of wild mammal species are updated from the 1998 version approved by the American Society of Mammalogists (ASM) and expanded to include additional resources. Included are details on marking, housing, trapping, and collecting mammals. These guidelines cover current professional techniques and regulations involving mammals used in research. Institutional animal care and use committees, regulatory agencies, and investigators should review and approve procedures concerning use of vertebrates at any particular institution. These guidelines were prepared and approved by the ASM, whose collective expertise provides a broad and comprehensive understanding of the biology of nondomesticated mammals in their natural environments.

3,979 citations

Journal ArticleDOI
05 Feb 1897-Science

3,125 citations

Journal ArticleDOI
TL;DR: A simple, non-invasive procedure that takes advantage of the strong near infrared (NIR) absorption of nanoshells, a new class of gold nanoparticles with tunable optical absorptivities that can undergo passive extravasation from the abnormal tumor vasculature due to their nanoscale size.

1,803 citations

Journal ArticleDOI
TL;DR: It is demonstrated that primates can learn to reach and grasp virtual objects by controlling a robot arm through a closed-loop brain–machine interface (BMIc) that uses multiple mathematical models to extract several motor parameters from the electrical activity of frontoparietal neuronal ensembles.
Abstract: Reaching and grasping in primates depend on the coordination of neural activity in large frontoparietal ensembles. Here we demonstrate that primates can learn to reach and grasp virtual objects by controlling a robot arm through a closed-loop brain–machine interface (BMIc) that uses multiple mathematical models to extract several motor parameters (i.e., hand position, velocity, gripping force, and the EMGs of multiple arm muscles) from the electrical activity of frontoparietal neuronal ensembles. As single neurons typically contribute to the encoding of several motor parameters, we observed that high BMIc accuracy required recording from large neuronal ensembles. Continuous BMIc operation by monkeys led to significant improvements in both model predictions and behavioral performance. Using visual feedback, monkeys succeeded in producing robot reach-and-grasp movements even when their arms did not move. Learning to operate the BMIc was paralleled by functional reorganization in multiple cortical areas, suggesting that the dynamic properties of the BMIc were incorporated into motor and sensory cortical representations.

1,740 citations

Journal ArticleDOI
TL;DR: Guidelines for use of wild mammal species in research are updated from Sikes et al. (2011), and include details on capturing, marking, housing, and humanely killing wild mammals.
Abstract: Guidelines for use of wild mammal species in research are updated from [Sikes et al. (2011)][1]. These guidelines cover current professional techniques and regulations involving the use of mammals in research and teaching; they also incorporate new resources, procedural summaries, and reporting requirements. Included are details on capturing, marking, housing, and humanely killing wild mammals. It is recommended that Institutional Animal Care and Use Committees (IACUCs), regulatory agencies, and investigators use these guidelines as a resource for protocols involving wild mammals, whether studied in the field or in captivity. These guidelines were prepared and approved by the American Society of Mammalogists (ASM), in consultation with professional veterinarians experienced in wildlife research and IACUCs, whose collective expertise provides a broad and comprehensive understanding of the biology of nondomesticated mammals. The current version of these guidelines and any subsequent modifications are available online on the Animal Care and Use Committee page of the ASM website ( ). Additional resources pertaining to the use of wild animals in research are available at: . Resumen Los lineamientos para el uso de especies de mamiferos de vida silvestre en la investigacion con base en [Sikes et al. (2011)][1] se actualizaron. Dichos lineamientos cubren tecnicas y regulaciones profesionales actuales que involucran el uso de mamiferos en la investigacion y ensenanza; tambien incorporan recursos nuevos, resumenes de procedimientos y requisitos para reportes. Se incluyen detalles acerca de captura, marcaje, manutencion en cautiverio y eutanasia de mamiferos de vida silvestre. Se recomienda que los comites institucionales de uso y cuidado animal (cifras en ingles: IACUCs), las agencias reguladoras y los investigadores se adhieran a dichos lineamientos como fuente base de protocolos que involucren mamiferos de vida silvestre, ya sea investigaciones de campo o en cautiverio. Dichos lineamientos fueron preparados y aprobados por la ASM, en consulta con profesionales veterinarios experimentados en investigaciones de vida silvestre y IACUCS, de quienes cuya experiencia colectiva provee un entendimiento amplio y exhaustivo de la biologia de mamiferos no-domesticados. La presente version de los lineamientos y modificaciones posteriores estan disponibles en linea en la pagina web de la ASM, bajo Cuidado Animal y Comite de Uso: ( ). Recursos adicionales relacionados con el uso de animales de vida silvestre para la investigacion se encuentran disponibles en ( ). [1]: #ref-69

1,728 citations