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Dmitriy M. Volochnyuk
Researcher at Enamine Ltd
Publications - 222
Citations - 2130
Dmitriy M. Volochnyuk is an academic researcher from Enamine Ltd. The author has contributed to research in topics: Chemistry & Trifluoromethyl. The author has an hindex of 23, co-authored 198 publications receiving 1636 citations. Previous affiliations of Dmitriy M. Volochnyuk include Taras Shevchenko National University of Kyiv & National Academy of Sciences of Ukraine.
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Journal ArticleDOI
Bicyclic Conformationally Restricted Diamines
Oleksandr O. Grygorenko,Oleksandr O. Grygorenko,Dmytro S. Radchenko,Dmytro S. Radchenko,Dmitriy M. Volochnyuk,Andrey A. Tolmachev,Andrey A. Tolmachev,Igor V. Komarov,Igor V. Komarov +8 more
TL;DR: In this paper, the authors propose a method to solve the problem of the problem: this paper...,.. ].. ).. ]... )...
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The Symbiotic Relationship Between Drug Discovery and Organic Chemistry.
Oleksandr O. Grygorenko,Oleksandr O. Grygorenko,Dmitriy M. Volochnyuk,Dmitriy M. Volochnyuk,Dmitriy M. Volochnyuk,Sergey V. Ryabukhin,Sergey V. Ryabukhin,Duncan B. Judd +7 more
TL;DR: Criteria for a high-quality compound library design enabling efficient virtual navigation of chemical space, as well as rise and fall of concepts for its synthetic exploration (such as combinatorial chemistry, diversity-, biology-, lead-, or fragment-oriented syntheses, DNA-encoded libraries etc.) are critically surveyed.
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Combinatorial Knoevenagel reactions.
Sergey V. Ryabukhin,Andrey S. Plaskon,Dmitriy M. Volochnyuk,Sergey E. Pipko,Alexander Shivanyuk,Andrey A. Tolmachev +5 more
TL;DR: Chlorotrimethylsilane (TMSCl) has been utilized as an efficient promoter and water scavenger in the Knoevenagel condensations of aromatic aldehydes with various methylene active compounds.
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Electron-Rich Amino Heterocycles for Regiospecific Synthesis of Trifluoromethyl-Containing Fused Pyridines
Dmitriy M. Volochnyuk,Alexei Pushechnikov,Dmitriy G. Krotko,Dmitriy A. Sibgatulin,Svetlana A. Kovalyova,Andrei A. Tolmachev +5 more
TL;DR: In this paper, a simple and flexible general procedure for the regiospecific annulation of the trifluoromethylpyridine ring to electron-rich amino heterocycles was proposed.
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Synthesis of Trifluoromethyl-Substituted 3-Azabicyclo[n.1.0]alkanes: Advanced Building Blocks for Drug Discovery
Olexiy S. Artamonov,Evgeniy Y. Slobodyanyuk,Dmitriy M. Volochnyuk,Igor V. Komarov,Andrey A. Tolmachev,Andrey A. Tolmachev,Pavel K. Mykhailiuk,Pavel K. Mykhailiuk +7 more
TL;DR: In this article, five CF3-substituted 3-azabicyclo[n.1.0]alkanes were synthesized by CuCl-mediated trifluoromethylcyclopropanation reaction of the corresponding cyclic enamides with CF3CHN2.