Dominik Eichin

TL;DR: These data indicate that, in contrast to other major leukocyte subpopulations, CD73 activity on macrophages does not play a major role in their polarization and that in mice host CD73 on any cell type is not required in vivo for peritoneal macrophage polarization towards either a pro- or an anti-inflammatory direction.

TL;DR: In this article, the authors demonstrated that Clever-1 is immunosuppressive towards migrating dendritic cells and thus regulates the magnitude of immune responses created by incoming DCs in the draining lymph nodes.

TL;DR: The findings suggested that harnessing the interplay between synthesis and self-assembly in complex chemical systems could yield functional nanomaterials for advanced applications.

TL;DR: It is revealed that a previously unknown role of CD73 on afferent lymphatics is to dampen immune responses, and a low likelihood of endothelial cell–related adverse effects by CD73 targeting therapeutic antibodies is indicated.

TL;DR: In this article, the authors evaluated whether N,N-diethyl-2-(2-(4-([18F]fluoro)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide (F-DPA) can reflect radiotherapy-induced changes in TSPO activity in head and neck squamous cell carcinoma (HNSCC).