Showing papers by "Donald Maxwell Parkin published in 1991"

Ethnicity and cancer risk in São Paulo, Brazil.

Abstract: Data from the Sao Paulo Cancer Registry (Brazil) for the period 1969-1974 are used to investigate ethnic differentials in cancer risk. Risks for specific cancers were estimated for mulattos and blacks relative to whites, using a case-control approach with other cancers as controls. For both sexes, blacks and mulattos are at higher risk than whites for cancer of the esophagus, stomach, and liver and for myeloma; for prostate cancer in males; and for gall bladder, pancreas, and cervix uteri cancers in females. Blacks and mulattos are at lower risk than whites for cancer of the colon, lung, larynx (males only), bladder, bone, testis, breast, and corpus uteri and for melanoma and leukemia. Except for lung and colon cancers, for which life-style habits are the main risk factors, these ethnic differences are similar to those observed in the United States.

Cancer in Italian migrants.

Abstract: Migration of Italians to other parts of the world has a long history and has involved very large numbers of individuals. The study of the health consequences of this migration is made possible by the availability of statistics on mortality and morbidity, both in Italy and in the host countries, and of social and economic information on the various Italian communities abroad. The results of the major studies are reviewed, comparing the rates in immigrants with those in the host countries and in Italy. The differences in cancer rates between Italian and local-born populations--for stomach cancer in both sexes, and for cancer of the colon, lung, and breast in females, and for prostate cancer--are consistent with the direction of differences between rates in Italy and those in the host countries. For colon and rectum cancer in males, there are unexpected findings in most of the United States' studies. Analysis by duration of residence shows changes in the risk for several sites in males, but not in females, according to length of stay in the host country. This finding possibly reflects greater stability of habits and lifestyle in females compared to males.

Cancer in migrants to Argentina.

Abstract: Mortality rates from different cancers in migrants to Argentina from 11 individual countries and 6 groups of countries were compared with those in the Argentina-born population and in their countries of origin. Almost all countries of origin had higher mortality rates from gastric cancer than Argentina, but the risk declines in migrants, and for European migrants becomes similar to that of the Argentina-born. In contrast, mortality from oesophageal cancer is significantly lower in European countries than in Argentina. For cancer of the colon and breast, most countries have lower mortality rates than the Argentina-born, the exceptions being Uruguay and Germany, and migrants demonstrate a convergence of risk towards that of Argentina-born. These results suggest that migrants to Argentina undergo changes in some environmental exposure, probably dietary, which give rise to substantial alterations in cancer risk within their lifespan.

Cancer Incidence in Western Samoa

Abstract: This report presents the first data on cancer incidence in Western Samoa, which has one of the largest Polynesian communities in the world. Incidence estimates are based on a systematic retrospective survey of cancer cases identified in the laboratory of pathology, and from hospital records, for the period January 1980 to June 1988. The overall incidence rates are low in both sexes (age-standardized incidence rates are 93.7 for males and 95.7 per 100,000 for females). Although cases may have been missed, it seems likely that incidence rates among Samoans are substantially lower than those recorded in Polynesian populations elsewhere. It is notable that cancers related to tobacco are responsible for less than 17% of all cancers in males, compared to more than 30% in other Polynesians. Stomach cancer remains the most common cancer in males. In females, breast and cervix are equally common and make up almost 40% of all cancers. Liver cancer occurs more commonly in males, and the rates are slightly lower than those of other Polynesians. The high incidence of thyroid cancer seen in some Pacific Island populations is not seen among Samoans.

Ethnicity and Cancer Risk in S#{227}o Paulo, Brazil

Abstract: Data from the S#{227}o Paulo Cancer Registry (Brazil) for the period 1969-1974 are used to investigate ethnic differentials in cancer risk. Risks for specific cancers were estimated for mulattos and blacks relative to whites, using a case-control approach with other cancers as controls. For both sexes, blacks and mulattos are at higher risk than whites for cancer of the esophagus, stomach, and liver and for myeloma; for prostate cancer in males; and for gall bladder, pancreas, and cervix uteri cancers in females. Blacks and mulattos are at lower risk than whites for cancer of the colon, lung, larynx (males only), bladder, bone, testis, breast, and corpus uteri and for melanoma and leukemia. Except for lung and colon cancers, for which life-style habits are the main risk fadors, these ethnic differences are similar to those observed in the United States.