Dong Wang

Bio: Dong Wang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Scanning tunneling microscope & Medicine. The author has an hindex of 49, co-authored 491 publications receiving 9970 citations. Previous affiliations of Dong Wang include University of Science and Technology of China & Shanghai University.

One-Step High-Temperature-Synthesized Single-Atom Platinum Catalyst for Efficient Selective Hydrogenation.

Abstract: Although single-atom catalysts significantly improve the atom utilization efficiency, the multistep preparation procedures are complicated and difficult to control. Herein, we demonstrate that one-step in situ synthesis of the single-atom Pt anchored in single-crystal MoC (Pt1/MoC) by using facile and controllable arc-discharge strategy under extreme conditions. The high temperature (up to 4000°C) provides the sufficient energy for atom dispersion and overall stability by forming thermodynamically favourable metal-support interactions. The high-temperature-stabilized Pt1/MoC exhibits outstanding performance and excellent thermal stability as durable catalyst for selective quinoline hydrogenation. The initial turnover frequency of 3710 h-1 is greater than those of previously reported samples by an order of magnitude under 2 MPa H2 at 100°C. The catalyst also shows broad scope activity toward hydrogenation containing unsaturated groups of C=C, C=N, and C=O. The facile, one-step, and fast arc-discharge method provides an effective avenue for single-atom catalyst fabrication that is conventionally challenging.

Site-Specific Construction of Long-Term Drug Depot for Suppression of Tumor Recurrence

Abstract: Local tumor recurrence after surgical resection is a critical concern in cancer therapy, and the current treatments, such as postsurgical chemotherapy, still show undesired side effects. Here a nonimplant strategy (transformation induced localization, TIL) is presented to in situ construct long-term retentive drug depots, wherein the sustained drug release from fibrous drug depots results in highly efficient suppression of postsurgical local tumor relapse. The peptide-based prodrug nanoparticles show favorable tumor targeting and instantly reorganize into fibrous nanostructures under overexpressed enzyme, realizing the construction of long-term drug depot in the tumor site. After the resection surgery, the remnant cancer cells are still inhibited by the sustained drug release from the fibrous prodrug depot, effectively preventing postsurgical local recurrences. This TIL strategy shows great potential in cancer recurrence therapy and offers a novel perspective for constructing functional biomaterials in vivo.

Adsorption mode of cinchonidine on Cu(111) surface.

Abstract: The adsorption mode of cinchonidine on Cu(111) was directly obtained by in situ STM. The molecules were found to adsorb on the substrate surface and form a long-range ordered adlayer with (4 × 4) symmetry. While the quinoline rings lie parallel to Cu(111), the chiral quinuclidine moiety extends out of the surface. The enantioselectivity of catalysts may relate to this special adsorption conformation of cinchonidine on the surface.

Supramolecular Complexes of C80-Based Metallofullerenes with [12]Cycloparaphenylene Nanoring and Altered Property in a Confined Space

Abstract: Metallofullerenes have a cage-shaped molecular structure and special properties derived from encapsulated metal atoms. Owing to the ball-like fullerene cage, it is still a challenge to manipulate the metallofullerene molecule and to control its properties. Herein, we use the molecular carbon nanoring of [12]cycloparaphenylene to hoop the C80-based metallofullerene Y3N@C80 and azafullerene Y2@C79N, resulting in a stable supramolecular complex, induced molecule orientation, changed assembly behavior, and tunable spin state. These supramolecular complexes and their host–guest interactions were systematically characterized by DFT-calculations, spectroscopy, NMR, and electrochemical analysis. Scanning tunneling microscopy was employed to reveal that the metallofullerene guests dominate the assembly process on the Au(111) surface and the [12]CPP nanoring can change the weak van der Waals forces and influence self-assembly. Moreover, the electron spin in paramagnetic Y2@C79N was employed to percept the host–gues...

Shedding light on the cell biology of extracellular vesicles.

Abstract: Extracellular vesicles are a heterogeneous group of cell-derived membranous structures comprising exosomes and microvesicles, which originate from the endosomal system or which are shed from the plasma membrane, respectively They are present in biological fluids and are involved in multiple physiological and pathological processes Extracellular vesicles are now considered as an additional mechanism for intercellular communication, allowing cells to exchange proteins, lipids and genetic material Knowledge of the cellular processes that govern extracellular vesicle biology is essential to shed light on the physiological and pathological functions of these vesicles as well as on clinical applications involving their use and/or analysis However, in this expanding field, much remains unknown regarding the origin, biogenesis, secretion, targeting and fate of these vesicles

Toward Safe Lithium Metal Anode in Rechargeable Batteries: A Review.

Abstract: The lithium metal battery is strongly considered to be one of the most promising candidates for high-energy-density energy storage devices in our modern and technology-based society. However, uncontrollable lithium dendrite growth induces poor cycling efficiency and severe safety concerns, dragging lithium metal batteries out of practical applications. This review presents a comprehensive overview of the lithium metal anode and its dendritic lithium growth. First, the working principles and technical challenges of a lithium metal anode are underscored. Specific attention is paid to the mechanistic understandings and quantitative models for solid electrolyte interphase (SEI) formation, lithium dendrite nucleation, and growth. On the basis of previous theoretical understanding and analysis, recently proposed strategies to suppress dendrite growth of lithium metal anode and some other metal anodes are reviewed. A section dedicated to the potential of full-cell lithium metal batteries for practical applicatio...

Recent Advances in Ultrathin Two-Dimensional Nanomaterials

Abstract: Since the discovery of mechanically exfoliated graphene in 2004, research on ultrathin two-dimensional (2D) nanomaterials has grown exponentially in the fields of condensed matter physics, material science, chemistry, and nanotechnology. Highlighting their compelling physical, chemical, electronic, and optical properties, as well as their various potential applications, in this Review, we summarize the state-of-art progress on the ultrathin 2D nanomaterials with a particular emphasis on their recent advances. First, we introduce the unique advances on ultrathin 2D nanomaterials, followed by the description of their composition and crystal structures. The assortments of their synthetic methods are then summarized, including insights on their advantages and limitations, alongside some recommendations on suitable characterization techniques. We also discuss in detail the utilization of these ultrathin 2D nanomaterials for wide ranges of potential applications among the electronics/optoelectronics, electrocat...

Active sites of nitrogen-doped carbon materials for oxygen reduction reaction clarified using model catalysts

Abstract: Nitrogen (N)-doped carbon materials exhibit high electrocatalytic activity for the oxygen reduction reaction (ORR), which is essential for several renewable energy systems. However, the ORR active site (or sites) is unclear, which retards further developments of high-performance catalysts. Here, we characterized the ORR active site by using newly designed graphite (highly oriented pyrolitic graphite) model catalysts with well-defined π conjugation and well-controlled doping of N species. The ORR active site is created by pyridinic N. Carbon dioxide adsorption experiments indicated that pyridinic N also creates Lewis basic sites. The specific activities per pyridinic N in the HOPG model catalysts are comparable with those of N-doped graphene powder catalysts. Thus, the ORR active sites in N-doped carbon materials are carbon atoms with Lewis basicity next to pyridinic N.

Recent Advances in Electrocatalysts for Oxygen Reduction Reaction

Abstract: The recent advances in electrocatalysis for oxygen reduction reaction (ORR) for proton exchange membrane fuel cells (PEMFCs) are thoroughly reviewed. This comprehensive Review focuses on the low- and non-platinum electrocatalysts including advanced platinum alloys, core–shell structures, palladium-based catalysts, metal oxides and chalcogenides, carbon-based non-noble metal catalysts, and metal-free catalysts. The recent development of ORR electrocatalysts with novel structures and compositions is highlighted. The understandings of the correlation between the activity and the shape, size, composition, and synthesis method are summarized. For the carbon-based materials, their performance and stability in fuel cells and comparisons with those of platinum are documented. The research directions as well as perspectives on the further development of more active and less expensive electrocatalysts are provided.