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Dongling Yang
Researcher at Chinese Academy of Sciences
Publications - 70
Citations - 8104
Dongling Yang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Angiogenesis & CD146. The author has an hindex of 27, co-authored 70 publications receiving 6335 citations. Previous affiliations of Dongling Yang include Kunming Institute of Zoology & Chinese Academy of Fishery Sciences.
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Journal ArticleDOI
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Lizeng Gao,Jie Zhuang,Leng Nie,Jinbin Zhang,Yu Zhang,Ning Gu,Taihong Wang,Jing Feng,Dongling Yang,Sarah Perrett,Xiyun Yan +10 more
TL;DR: It is reported that magnetite nanoparticles in fact possess an intrinsic enzyme mimetic activity similar to that found in natural peroxidases, which are widely used to oxidize organic substrates in the treatment of wastewater or as detection tools.
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Magnetoferritin nanoparticles for targeting and visualizing tumour tissues
Kelong Fan,Changqian Cao,Yongxin Pan,Di Lu,Dongling Yang,Jing Feng,Lina Song,Minmin Liang,Xiyun Yan +8 more
TL;DR: In this article, magnetoferritin nanoparticles (M-HFn) are used to target and visualize tumour tissues without the use of any targeting ligands or contrast agents, which can distinguish cancerous cells from normal cells with a sensitivity of 98% and specificity of 95%.
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H-ferritin-nanocaged doxorubicin nanoparticles specifically target and kill tumors with a single-dose injection.
TL;DR: It is shown that natural H-ferritin (HFn) nanocages can carry high doses of doxorubicin (Dox) for tumor-specific targeting and killing without any targeting ligand functionalization or property modulation, which makes the HFn nanocage an ideal vehicle for efficient anticancer drug delivery.
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Fe3O4 magnetic nanoparticle peroxidase mimetic-based colorimetric assay for the rapid detection of organophosphorus pesticide and nerve agent.
Minmin Liang,Kelong Fan,Yong Pan,Hui Jiang,Fei Wang,Dongling Yang,Di Lu,Jing Feng,Jianjun Zhao,Liu Yang,Xiyun Yan +10 more
TL;DR: By employing the peroxidase-mimicking activity of MNPs, the developed colorimetric assay has the potential of becoming a screening tool for the rapid and sensitive assessment of the neurotoxicity of an overwhelming number of organophosphate compounds.
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A novel anti-CD146 monoclonal antibody, AA98, inhibits angiogenesis and tumor growth
Xiyun Yan,Yun Lin,Dongling Yang,Yi Shen,Mei Yuan,Zhiqiang Zhang,Peiyu Li,Hongtian Xia,Li Li,Dandan Luo,Qin Liu,Karlheinz Mann,Bernhard L. Bader +12 more
TL;DR: The data provide new insights into the function of CD146 on endothelial cells, validate CD146 as a novel target for antiangiogenic agents, and demonstrate that mAb AA98 has potential as a diagnostic and therapeutic agent in vascular and cancer biology.