D
Dongwon Yoo
Researcher at Seoul National University
Publications - 68
Citations - 5682
Dongwon Yoo is an academic researcher from Seoul National University. The author has contributed to research in topics: Electrolyte & Chemistry. The author has an hindex of 21, co-authored 62 publications receiving 4884 citations. Previous affiliations of Dongwon Yoo include University of California & Office of Technology Transfer.
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Journal ArticleDOI
Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
Chris Tran,Samedy Ouk,Nicola J. Clegg,Yu Chen,Philip A. Watson,Vivek K. Arora,John Wongvipat,Peter Smith-Jones,Dongwon Yoo,Andrew Kwon,Teresa Wasielewska,Derek S. Welsbie,Charlie D. Chen,Celestia S. Higano,Tomasz M. Beer,David T. Hung,Howard I. Scher,Michael E. Jung,Charles L. Sawyers +18 more
TL;DR: The diarylthiohydantoins RD162 and MDV3100 are characterized, two compounds optimized from a screen for nonsteroidal antiandrogens that retain activity in the setting of increased androgen receptor expression that appear to be promising candidates for treatment of advanced prostate cancer.
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Iron Oxide Based Nanoparticles for Multimodal Imaging and Magnetoresponsive Therapy.
TL;DR: Magnetoresponsive Therapy Nohyun Lee, Dongwon Yoo, Daishun Ling,†,‡,⊥ Mi Hyeon Cho, Taeghwan H Yeon,*,†,† and Jinwoo Cheon.
Journal ArticleDOI
Theranostic magnetic nanoparticles
TL;DR: The use of magnetic nanoparticles to drive mechanical forces is demonstrated to be useful for molecular-level cell signaling and for controlling the ultimate fate of the cell.
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Structure−Activity Relationship for Thiohydantoin Androgen Receptor Antagonists for Castration-Resistant Prostate Cancer (CRPC)
Michael E. Jung,Samedy Ouk,Dongwon Yoo,Charles L. Sawyers,Charlie Chen,Chris Tran,John Wongvipat +6 more
TL;DR: A structure-activity relationship study was carried out on a series of thiohydantoins and their analogues 14 which led to the discovery of 92 (MDV3100) as the clinical candidate for the treatment of hormone refractory prostate cancer.
Journal ArticleDOI
A magnetic switch for the control of cell death signalling in in vitro and in vivo systems
Mi Hyeon Cho,Eun Jung Lee,Mina Son,Jae Hyun Lee,Dongwon Yoo,Ji Wook Kim,Seung-Woo Park,Jeon Soo Shin,Jinwoo Cheon +8 more
TL;DR: This work has developed magnetic nanoparticles that turn on apoptosis cell signalling by using a magnetic field in a remote and non-invasive manner and can be applied in an in vivo system where apoptotic morphological changes of zebrafish are successfully induced.