D
Douglas B. Kell
Researcher at University of Liverpool
Publications - 657
Citations - 55792
Douglas B. Kell is an academic researcher from University of Liverpool. The author has contributed to research in topics: Systems biology & Dielectric. The author has an hindex of 111, co-authored 634 publications receiving 50335 citations. Previous affiliations of Douglas B. Kell include Max Planck Society & University of Wales.
Papers
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Journal ArticleDOI
A systematic approach to modeling, capturing, and disseminating proteomics experimental data.
Chris F. Taylor,Norman W. Paton,Kevin Garwood,P. Kirby,David Stead,Zhikang Yin,Eric W. Deutsch,Laura Selway,Janet Walker,Isabel Riba-Garcia,Shabaz Mohammed,Michael J. Deery,Julie Howard,Tom Dunkley,Ruedi Aebersold,Douglas B. Kell,Kathryn S. Lilley,Peter Roepstorff,John R. Yates,Andy Brass,Alistair J. P. Brown,Phil Cash,Simon J. Gaskell,Simon J. Hubbard,Stephen G. Oliver +24 more
TL;DR: A UML (unified modeling language) approach to proteomics experimental data is presented, XML and SQL (structured query language) implementations of that model are described, and capture, storage, and dissemination strategies are discussed.
Journal ArticleDOI
Event extraction for systems biology by text mining the literature.
TL;DR: This review summarizes the methods that are currently available, with a specific focus on protein-protein interactions and pathway or network reconstruction, and will be of considerable value in associating particular pathways and their components with higher-order physiological properties, including disease states.
Patent
Determination of biomass
Douglas B. Kell,Robert W. Todd +1 more
TL;DR: In this article, an approach for the determination of biomass in a suspension and its use in a fermentation apparatus is presented. But this approach is not suitable for the measurement of the current in the current electrode circuit and the ratio between the values of the voltage signal and the value of a quadrature component of the signal.
Journal ArticleDOI
Recon 2.2: from reconstruction to model of human metabolism
Neil Swainston,Kieran Smallbone,Hooman Hefzi,Paul D. Dobson,Judy Brewer,Michael Hanscho,Daniel C. Zielinski,Kok Siong Ang,Natalie J. Gardiner,Jahir M. Gutierrez,Sarantos Kyriakopoulos,Meiyappan Lakshmanan,Shangzhong Li,Joanne K. Liu,Veronica Martinez,Camila A. Orellana,Lake-Ee Quek,Alex Thomas,Juergen Zanghellini,Nicole Borth,Dong-Yup Lee,Dong-Yup Lee,Lars K. Nielsen,Douglas B. Kell,Nathan E. Lewis,Pedro Mendes +25 more
TL;DR: The human genome-scale metabolic reconstruction details all known metabolic reactions occurring in humans, and thereby holds substantial promise for studying complex diseases and phenotypes as discussed by the authors, and since the last community effort generated a consensus reconstruction, several updates have been developed.
Journal ArticleDOI
Large-scale sequestration of atmospheric carbon via plant roots in natural and agricultural ecosystems: why and how.
TL;DR: Breeding crops with desirable below-ground C sequestration traits, and exploiting attendant agronomic practices optimised for individual species in their relevant environments, are important goals.