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Drake G. LeBrun

Researcher at University of Pennsylvania

Publications -  39
Citations -  963

Drake G. LeBrun is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 13, co-authored 22 publications receiving 814 citations. Previous affiliations of Drake G. LeBrun include University of Texas Health Science Center at Houston & University of Texas Southwestern Medical Center.

Papers
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Journal ArticleDOI

Deregulated signaling pathways in glioblastoma multiforme: molecular mechanisms and therapeutic targets.

Hua Mao, +4 more
- 31 Jan 2012 - 
TL;DR: The most common and important pathways that are highly mutated or deregulated in GBM are summarized and potential therapeutic strategies targeting these pathways are discussed.
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Overcoming drug resistance in pancreatic cancer

Jiang Long, +7 more
- 09 Jun 2011 - 
TL;DR: This review summarizes recent advances in the mechanisms of drug resistance in pancreatic cancer and potential strategies to overcome this and recommends novel therapeutic strategies to increase the efficacy of current treatments in a wide variety of human cancers.
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Prioritizing essential surgery and safe anesthesia for the Post-2015 Development Agenda: Operative capacities of 78 district hospitals in 7 low- and middle-income countries

Drake G. LeBrun, +7 more
- 01 Mar 2014 - 
TL;DR: The need for operative procedures is not being met by the limited operative capacity in numerous low- and middle-income countries and it is of paramount importance that this gap be addressed by prioritizing essential surgery and safe anesthesia in the Post-2015 Development Agenda.
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Understanding the role of cytokines in Glioblastoma Multiforme pathogenesis.

Vivian F. Zhu, +3 more
- 28 Mar 2012 - 
TL;DR: This review summarizes the current understanding of the functions of key cytokines on Glioblastoma Multiforme, and highlights potential therapeutic applications targeting these cytokines.
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Liberian Surgical and Anesthesia Infrastructure: A Survey of County Hospitals

Lisa M. Knowlton, +6 more
- 13 Feb 2013 - 
TL;DR: There is strong evidence for continued development of emergency and essential surgical services, as well as improved surgical outcomes tracking, at county hospitals in Liberia, and the density and quality of appropriately trained personnel and infrastructure remain critically low.