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Durairaj Siva

Bio: Durairaj Siva is an academic researcher from Bharathidasan University. The author has contributed to research in topics: Silver nanoparticle & Silver nitrate. The author has an hindex of 7, co-authored 12 publications receiving 446 citations.

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TL;DR: The current study elucidates that the synthesized AgNPs were efficient against the bacterial strains tested and showed an obvious superiority of the antibacterial potency of BAgNPs compared to the CAgNPs as denoted by the zone of inhibition (ZoI).

121 citations

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TL;DR: In vitro radical scavenging assay proved strong antioxidant effect of the AgNPs compared to 5% aqueous leaf extract, indicating the curing effects on CCl(4) induced liver injury.

113 citations

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TL;DR: Hematological and biochemical analyses revealed revival after treating with F. religiosa derived AgNPs, and anti- angiogenic activity was confirmed by observing vessel development, indicate that theAgNPs were effective in treatment of DAL.

87 citations

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TL;DR: Results from this study suggested that Streptomyces sp.

83 citations

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TL;DR: In vivo analysis of biochemical parameters and histological architecture provided evidence for the antibacterial effect of AgNPs in the fish model and inductively coupled plasmon optical emission spectroscopy revealed particles with superior stability.

55 citations


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01 Aug 2000
TL;DR: Assessment of medical technology in the context of commercialization with Bioentrepreneur course, which addresses many issues unique to biomedical products.
Abstract: BIOE 402. Medical Technology Assessment. 2 or 3 hours. Bioentrepreneur course. Assessment of medical technology in the context of commercialization. Objectives, competition, market share, funding, pricing, manufacturing, growth, and intellectual property; many issues unique to biomedical products. Course Information: 2 undergraduate hours. 3 graduate hours. Prerequisite(s): Junior standing or above and consent of the instructor.

4,833 citations

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TL;DR: The plants are used successfully in the synthesis of various greener nanoparticles such as cobalt, copper, silver, gold, palladium, platinum, zinc oxide and magnetite, and the biological synthesis of metallic nanoparticles is inexpensive, single step and eco-friendly methods.
Abstract: The field of nanotechnology mainly encompasses with biology, physics, chemistry and material sciences and it develops novel therapeutic nanosized materials for biomedical and pharmaceutical applications. The biological syntheses of nanoparticles are being carried out by different macro-microscopic organisms such as plant, bacteria, fungi, seaweeds and microalgae. The biosynthesized nanomaterials have been effectively controlling the various endemic diseases with less adverse effect. Plant contains abundant natural compounds such as alkaloids, flavonoids, saponins, steroids, tannins and other nutritional compounds. These natural products are derived from various parts of plant such as leaves, stems, roots shoots, flowers, barks, and seeds. Recently, many studies have proved that the plant extracts act as a potential precursor for the synthesis of nanomaterial in non-hazardous ways. Since the plant extract contains various secondary metabolites, it acts as reducing and stabilizing agents for the bioreduction reaction to synthesized novel metallic nanoparticles. The non-biological methods (chemical and physical) are used in the synthesis of nanoparticles, which has a serious hazardous and high toxicity for living organisms. In addition, the biological synthesis of metallic nanoparticles is inexpensive, single step and eco-friendly methods. The plants are used successfully in the synthesis of various greener nanoparticles such as cobalt, copper, silver, gold, palladium, platinum, zinc oxide and magnetite. Also, the plant mediated nanoparticles are potential remedy for various diseases such as malaria, cancer, HIV, hepatitis and other acute diseases.

681 citations

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TL;DR: A green chemistry method for synthesized colloidal silver nanoparticles (Ag NPs) in polymeric media using silver nitrate, polyethylene glycol, and β-D-glucose as a silver precursor, stabilizer, and reducing agent is reported.
Abstract: The roles of green chemistry in nanotechnology and nanoscience fields are very significant in the synthesis of diverse nanomaterials. Herein, we report a green chemistry method for synthesized colloidal silver nanoparticles (Ag NPs) in polymeric media. The colloidal Ag NPs were synthesized in an aqueous solution using silver nitrate, polyethylene glycol (PEG), and β-D-glucose as a silver precursor, stabilizer, and reducing agent, respectively. The properties of synthesized colloidal Ag NPs were studied at different reaction times. The ultraviolet-visible spectra were in excellent agreement with the obtained nanostructure studies performed by transmission electron microscopy (TEM) and their size distributions. The Ag NPs were characterized by utilizing X-ray diffraction (XRD), zeta potential measurements and Fourier transform infrared (FT-IR). The use of green chemistry reagents, such as glucose, provides green and economic features to this work.

434 citations

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TL;DR: In this article, a review describes recent developments in the synthesis, modification and practical applications of nanoparticles (NPs) and also describes the methods of NPs incorporation in various matrices.

390 citations

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TL;DR: It is confirmed that the antibacterial effect of bare as well as TG capped ZnO NPs were due to membrane lipid peroxidation caused by the ROS generated during Zn O NPs interaction in culture medium.

371 citations