E
E. D. Gilles
Researcher at Max Planck Society
Publications - 46
Citations - 4103
E. D. Gilles is an academic researcher from Max Planck Society. The author has contributed to research in topics: Systems biology & Nonlinear system. The author has an hindex of 17, co-authored 46 publications receiving 3932 citations. Previous affiliations of E. D. Gilles include University of Stuttgart.
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Journal ArticleDOI
The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models.
Michael Hucka,Andrew Finney,Herbert M. Sauro,Hamid Bolouri,Hamid Bolouri,John Doyle,Hiroaki Kitano,Adam P. Arkin,Benjamin Bornstein,Dennis Bray,Athel Cornish-Bowden,Autumn A. Cuellar,S. Dronov,E. D. Gilles,Martin Ginkel,V. Gor,Igor Goryanin,W. J. Hedley,T. C. Hodgman,J.-H.S. Hofmeyr,Peter Hunter,Nick Juty,J. L. Kasberger,Andreas Kremling,Ursula Kummer,N Le Novère,Leslie M. Loew,D. Lucio,Pedro Mendes,E. Minch,Eric Mjolsness,Yoichi Nakayama,Melanie R. Nelson,Poul M. F. Nielsen,T. Sakurada,James C. Schaff,Bruce E. Shapiro,Thomas S. Shimizu,H. D. Spence,Jörg Stelling,Koichi Takahashi,Masaru Tomita,John Wagner,J. Wang +43 more
TL;DR: This work summarizes the Systems Biology Markup Language (SBML) Level 1, a free, open, XML-based format for representing biochemical reaction networks, a software-independent language for describing models common to research in many areas of computational biology.
Journal ArticleDOI
The organization of metabolic reaction networks. III. Application for diauxic growth on glucose and lactose.
Andreas Kremling,Katja Bettenbrock,Britta Laube,Knut Jahreis,Joseph W. Lengeler,E. D. Gilles +5 more
TL;DR: A mathematical model to describe carbon catabolite repression in Escherichia coli is developed and in part validated and all experiments could be sufficiently described with a single set of parameters.
Journal ArticleDOI
Modular analysis of signal transduction networks
Julio Saez-Rodriguez,Andreas Kremling,Holger Conzelmann,Katja Bettenbrock,E. D. Gilles,E. D. Gilles +5 more
TL;DR: The mechanisms that cells have developed to process information are described, and the decomposition of signalling networks into subsystems is discussed, and some simple criteria for the analysis of the resulting units are introduced.
Book ChapterDOI
Real-Time Optimization for Large Scale Processes: Nonlinear Model Predictive Control of a High Purity Distillation Column
Moritz Diehl,Ilknur Uslu,Rolf Findeisen,S. Schwarzkopf,Frank Allgöwer,Hans Georg Bock,T. Bürner,E. D. Gilles,Achim Kienle,Johannes P. Schlöder +9 more
TL;DR: An experimental proof-of-concept of the application of NMPC for large scale systems using specialized dynamic optimization strategies to a nontrivial process control example, namely the control of a high purity binary distillation column.
Journal ArticleDOI
The organization of metabolic reaction networks. II. Signal processing in hierarchical structured functional units.
Andreas Kremling,E. D. Gilles +1 more
TL;DR: Based on the analysis of molecular interactions of proteins with DNA binding sites, a new approach to developing mathematical models describing gene expression is introduced that will be used to decompose complex reaction schemes by assigning each regulator protein to one level in the hierarchy.