E. Reisenhofer

Bio: E. Reisenhofer is an academic researcher from University of Trieste. The author has contributed to research in topics: Free-energy relationship & Nucleophile. The author has an hindex of 2, co-authored 3 publications receiving 94 citations.

Reactions of cobalt(I) complexes with ammonium and sulphonium ions and organic halides

Abstract: Kinetic measurements are reported for the dealkylation reactions of ammonium and sulphonium compounds and organic halides with cobalt(I) complexes of a series of tetradentate Schiff's bases The reaction was followed by polarography and cyclic voltammetry The kinetics conformed to a second order rate law and pseudo-first order plots were obtained in the presence of an excess of substrate The plot of E½ values vs log k″ for the reaction with PhBr and EtBr and [Me2SC6H4Me]+ shows a linear free energy relationship suggesting a simple SN2 displacement reaction and confirming that the nucleophilicity of cobalt(I) species is influenced by the nature of the chelating ligands

Reactions of cobalt(i) complexes with ammonium and sulphonium ions and organic halides

Abstract: Kinetic measurements are reported for the dealkylation reactions of ammonium and sulphonium compounds and organic halides with cobalt(I) complexes of a series of tetradentate Schiff's bases. The reaction was followed by polarography and cyclic voltammetry. The kinetics conformed to a second order rate law and pseudo-first order plots were obtained in the presence of an excess of substrate. The plot of E½ values vs. log k″ for the reaction with PhBr and EtBr and [Me2SC6H4Me]+ shows a linear free energy relationship suggesting a simple SN2 displacement reaction and confirming that the nucleophilicity of cobalt(I) species is influenced by the nature of the chelating ligands.

Electroreductive Remediation of Halogenated Environmental Pollutants.

Abstract: Electrochemical reduction of halogenated organic compounds is gaining increasing attention as a strategy for the remediation of environmental pollutants. We begin this review by discussing key components (cells, electrodes, solvents, and electrolytes) in the design of a procedure for degrading a targeted pollutant, and we describe and contrast some experimental techniques used to explore and characterize the electrochemical behavior of that pollutant. Then, we describe how to probe various mechanistic features of the pertinent electrochemistry (including stepwise versus concerted carbon–halogen bond cleavage, identification of reaction intermediates, and elucidation of mechanisms). Knowing this information is vital to the successful development of a remediation procedure. Next, we outline techniques, instrumentation, and cell designs involved in scaling up a benchtop experiment to an industrial-scale system. Finally, the last and major part of this review is directed toward surveying electrochemical studi...

Selectivity among two lectins: probing the effect of topology, multivalency and flexibility of "clicked" multivalent glycoclusters.

Abstract: We have designed a series of multivalent galactosylated glycoconjugates and studied their binding properties towards two lectins, from plant and bacterial origins, to determine their potential selectivity. The synthesis was achieved through copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) under microwave activation between propargylated multivalent scaffolds and an azido-functionalised carbohydrate derivative. The interactions of two galactose-binding lectins from Pseudomonas aeruginosa (PA-IL) and Erythrina cristagalli (ECA) with the synthesized glycoclusters were studied by hemagglutination inhibition assays (HIA), surface plasmon resonance (SPR) and isothermal titration microcalorimetry (ITC). The results obtained illustrate the influence of the scaffold's geometry on the affinity towards the lectin and also on the relative potency in comparison with a monovalent galactoside reference probe.