E
E. Richard Stanley
Researcher at Albert Einstein College of Medicine
Publications - 183
Citations - 30738
E. Richard Stanley is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Macrophage colony-stimulating factor & Phosphorylation. The author has an hindex of 71, co-authored 180 publications receiving 27529 citations. Previous affiliations of E. Richard Stanley include Heidelberg University & University of Michigan.
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Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Florent Ginhoux,Florent Ginhoux,Melanie Greter,Marylene Leboeuf,Sayan Nandi,Peter See,Solen Gokhan,Mark F. Mehler,Simon J. Conway,Lai Guan Ng,E. Richard Stanley,Igor M. Samokhvalov,Miriam Merad +12 more
TL;DR: Results identify microglia as an ontogenically distinct population in the mononuclear phagocyte system and have implications for the use of embryonically derived microglial progenitors for the treatment of various brain disorders.
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Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes
Daigo Hashimoto,Andrew Chow,Andrew Chow,Clara Noizat,Clara Noizat,Pearline Teo,Mary Beth Beasley,Marylene Leboeuf,Christian Becker,Peter See,Jeremy Price,Daniel Lucas,Melanie Greter,Melanie Greter,Arthur Mortha,Scott W. Boyer,E. Camilla Forsberg,Masato Tanaka,Nico van Rooijen,Adolfo García-Sastre,E. Richard Stanley,Florent Ginhoux,Paul S. Frenette,Miriam Merad +23 more
TL;DR: Results indicate that tissue-resident macrophages and circulating monocytes should be classified as mononuclear phagocyte lineages that are independently maintained in the steady state.
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The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1
Charles J. Sherr,Carl W. Rettenmier,Rosalba Sacca,Martine F. Roussel,A. Thomas Look,E. Richard Stanley +5 more
TL;DR: The feline c-fms proto-oncogene product and the CSF-1 receptor are related, and possibly identical, molecules.
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A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors.
Jeffrey B. Wyckoff,Weigang Wang,Elaine Y. Lin,Yarong Wang,Fiona J. Pixley,E. Richard Stanley,Thomas Graf,Jeffrey W. Pollard,Jeffrey E. Segall,John S. Condeelis +9 more
TL;DR: This work provides the first direct evidence for a synergistic interaction between macrophages and tumor cells during cell migration in vivo and indicates a mechanism for how macrophage may contribute to metastasis.
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Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects.
Xuming Dai,Gregory R. Ryan,Andrew J. Hapel,Melissa G. Dominguez,Robert G. Russell,Sara Kapp,Vonetta Sylvestre,E. Richard Stanley +7 more
TL;DR: The results indicate that all of the effects of CSF-1 are mediated via the CSf-1R, but that subtle effects of the CS fms proto-oncogene could result from its CS F-1-independent activation.