E
E. Vigo
Researcher at University of Córdoba (Spain)
Publications - 15
Citations - 2022
E. Vigo is an academic researcher from University of Córdoba (Spain). The author has contributed to research in topics: Kisspeptin & Gonadotropin secretion. The author has an hindex of 15, co-authored 15 publications receiving 1936 citations.
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Journal ArticleDOI
Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition.
Juan M. Castellano,Víctor M. Navarro,R. Fernández-Fernández,Rubén Nogueiras,Sulay Tovar,Juan Carlos Roa,María Jesús Vázquez,E. Vigo,Felipe F. Casanueva,Enrique Aguilar,Leonor Pinilla,Carlos Dieguez,Manuel Tena-Sempere +12 more
TL;DR: The data are the first to show an interaction between energy status and the hypothalamic KiSS-1 system, which may constitute a target for disruption (and eventual therapeutic intervention) of pubertal development in conditions of negative energy balance.
Journal ArticleDOI
Expression of KiSS-1 in Rat Ovary: Putative Local Regulator of Ovulation?
Juan M. Castellano,María Gaytán,Juan Carlos Roa,E. Vigo,Víctor M. Navarro,Carmina Bellido,Carlos Dieguez,Enrique Aguilar,José E. Sánchez-Criado,Antonio Pellicer,Leonor Pinilla,F Gaytan,Manuel Tena-Sempere +12 more
TL;DR: The ability of the LH surge to timely induce ovarian expression of KiSS-1 at the preovulatory period strongly suggests a previously unsuspected role of locally produced kisspeptin in the control of ovulation.
Journal ArticleDOI
Expression of Hypothalamic KiSS-1 System and Rescue of Defective Gonadotropic Responses by Kisspeptin in Streptozotocin-Induced Diabetic Male Rats
Juan M. Castellano,Víctor M. Navarro,R. Fernández-Fernández,Juan Carlos Roa,E. Vigo,Rafael Pineda,Carlos Dieguez,Enrique Aguilar,Leonor Pinilla,Manuel Tena-Sempere +9 more
TL;DR: This observation, together with the ability of exogenous kisspeptin to rescue defective LH responses in diabetic rats, unravel the physiopathological implication, and potential therapeutic intervention, of the KiSS-1 system in altered gonadotropin secretion of type 1 diabetes.
Journal ArticleDOI
Hypothalamic Expression of KiSS-1 System and Gonadotropin-Releasing Effects of Kisspeptin in Different Reproductive States of the Female Rat
Juan Carlos Roa,E. Vigo,Juan M. Castellano,Víctor M. Navarro,R. Fernández-Fernández,Felipe F. Casanueva,Carlos Dieguez,Enrique Aguilar,Leonor Pinilla,Manuel Tena-Sempere +9 more
TL;DR: This work evaluated maximal LH and FSH secretory responses to kisspeptin-10, as well as changes in sensitivity and hypothalamic expression of KiSS-1 and GPR54 genes, in different physiological and experimental models in the adult female rat to document for the first time the changes in leptin expression and the gonadotropic effects in different functional states of the female reproductive axis.
Journal ArticleDOI
Comparative analysis of the effects of ghrelin and unacylated ghrelin on luteinizing hormone secretion in male rats.
A. C. Martini,R. Fernández-Fernández,Sulay Tovar,Víctor M. Navarro,E. Vigo,Marisol Vazquez,Jeffrey S. Davies,Nichola M. Thompson,Enrique Aguilar,Leonor Pinilla,Timothy N. C. Wells,Carlos Dieguez,M. Tena-Sempere,M. Tena-Sempere,M. Tena-Sempere +14 more
TL;DR: The contention that ghrelin, as putative signal for energy insufficiency, may operate as negative modifier of male puberty and LH secretion, an effect that might be, at least partially, conducted through a GH secretagogue receptor type 1a-independent mechanism is reinforced.