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E. Wesley Ely
Researcher at Vanderbilt University Medical Center
Publications - 560
Citations - 52051
E. Wesley Ely is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Delirium & Intensive care. The author has an hindex of 102, co-authored 504 publications receiving 43799 citations. Previous affiliations of E. Wesley Ely include Veterans Health Administration & Wake Forest University.
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Journal ArticleDOI
Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit
Juliana Barr,Gilles L. Fraser,Kathleen Puntillo,E. Wesley Ely,Céline Gélinas,Joseph F. Dasta,Judy E. Davidson,John W. Devlin,John P. Kress,Aaron M. Joffe,Douglas B. Coursin,Daniel Herr,Avery Tung,Bryce R.H. Robinson,Dorrie K. Fontaine,Michael A. E. Ramsay,Richard R. Riker,Curtis N. Sessler,Brenda T. Pun,Yoanna Skrobik,Roman Jaeschke +20 more
TL;DR: These guidelines provide a roadmap for developing integrated, evidence-based, and patient-centered protocols for preventing and treating pain, agitation, and delirium in critically ill patients.
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Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit
E. Wesley Ely,Ayumi Shintani,Brenda Truman,Theodore Speroff,Sharon M. Gordon,Frank E. Harrell,Sharon K. Inouye,Gordon R. Bernard,Robert S. Dittus +8 more
TL;DR: Delirium was an independent predictor of higher 6-month mortality and longer hospital stay even after adjusting for relevant covariates including coma, sedatives, and analgesics in patients receiving mechanical ventilation.
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Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis
TL;DR: Severe sepsis in this older population was independently associated with substantial and persistent new cognitive impairment and functional disability among survivors, likely resulting in a pivotal downturn in patients' ability to live independently.
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Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial
Timothy D. Girard,John P. Kress,Barry D. Fuchs,Jason W. W. Thomason,William D. Schweickert,Brenda T. Pun,Darren B. Taichman,Jan Dunn,Anne S. Pohlman,Paul Kinniry,James C. Jackson,Angelo E. Canonico,Richard W. Light,Ayumi Shintani,Jennifer L. Thompson,Sharon M. Gordon,Sharon M. Gordon,Jesse B. Hall,Robert S. Dittus,Robert S. Dittus,Gordon R. Bernard,E. Wesley Ely,E. Wesley Ely +22 more
TL;DR: It is suggested that a wake up and breathe protocol that pairs daily spontaneous awakening trials (ie, interruption of sedatives) with daily spontaneous breathing trials results in better outcomes for mechanically ventilated patients in intensive care than current standard approaches and should become routine practice.
Journal ArticleDOI
Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS).
E. Wesley Ely,Brenda Truman,Ayumi Shintani,Jason W. W. Thomason,Arthur P. Wheeler,Sharon M. Gordon,Joseph Francis,Theodore Speroff,Shiva Gautam,Richard Margolin,Curtis N. Sessler,Robert S. Dittus,Gordon R. Bernard +12 more
TL;DR: This is the first sedation scale to be validated for its ability to detect changes in sedation status over consecutive days of ICU care, against constructs of level of consciousness and delirium, and correlated with the administered dose of sedative and analgesic medications.