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Ed Lakatos

Bio: Ed Lakatos is an academic researcher. The author has contributed to research in topics: Weight loss & Blood pressure. The author has an hindex of 1, co-authored 1 publications receiving 694 citations.

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Journal ArticleDOI
Paul K. Whelton, Lawrence J. Appel, Jeanne Charleston, Arlene Taylor Dalcin, Craig K. Ewart, Linda P. Fried, Delores Kaidy, Michael J. Klag, Shiriki K. Kumanyika, Lyn Steffen, W. Gordon Walker, Albert Oberman, Karen Counts, Heidi Hataway, James M. Raczynski, Neil Rappaport, Roland Weinsier, Nemat O. Borhani, Edmund Bernauer, Patricia A. Borhani, Carlos de la Cruz, Andrew Ertl, Doug Heustis, Marshall Lee, Wade Lovelace, Ellen O'Connor, Liz Peel, Carolyn Sugars, James O. Taylor, Beth Walker Corkery, Denis A. Evans, Mary Ellen Keough, Martha Clare Morris, Eleanor Pistorino, Frank M. Sacks, Mary Cameron, Sheila Corrigan, Nancy King Wright, William B. Applegate, Amy Brewer, Laretha Goodwin, Stephen T. Miller, Joseph T. Murphy, Judy Randle, Jay M. Sullivan, Norman L. Lasser, David M. Batey, Lee Dolan, Sheila Hamill, Pat Kennedy, Vera I. Lasser, Lewis H. Kuller, Arlene W. Caggiula, N. Carole Milas, Monica E. Yamamoto, Thomas M. Vogt, Merwyn R. Greenlick, Jack F. Hollis, Victor J. Stevens, Jerome D. Cohen, Mildred Mattfeldt-Beman, Connie Brinkmann, Katherine Roth, Lana Shepek, Charles H. Hennekens, Julie E. Buring, Nancy R. Cook, Ellie Danielson, Kim Eberlein, David Gordon, Patricia R. Hebert, Jean MacFadyen, Sherry L. Mayrent, Bernard Rosner, Suzanne Satterfield, Heather Tosteson, Martin Van Denburgh, Jeffrey A. Cutler, Erica Brittain, Marilyn Farrand, Peter G. Kaufmann, Ed Lakatos, Eva Obarzanek, John Belcher, Andrea Dommeyer, Ivan Mills, Peggy Neibling, Margo Woods, B.J. Kremen Goldman, Elaine Blethen 
04 Mar 1992-JAMA
TL;DR: Weight reduction is the most effective of the strategies tested for reducing blood pressure in normotensive persons, and sodium reduction is also effective.
Abstract: Objective. —To test the short-term feasibility and efficacy of seven nonpharmacologic interventions in persons with high normal diastolic blood pressure. Design. —Randomized control multicenter trials. Setting. —Volunteers recruited from the community, treated and followed up at special clinics. Participants. —Of 16821 screenees, 2182 men and women, aged 30 through 54 years, with diastolic blood pressure from 80 through 89 mm Hg were selected. Of these, 50 did not return for follow-up blood pressure measurements. Interventions. —Three life-style change groups (weight reduction, sodium reduction, and stress management) were each compared with unmasked nonintervention controls over 18 months. Four nutritional supplement groups (calcium, magnesium, potassium, and fish oil) were each compared singly, in double-blind fashion, with placebo controls over 6 months. Main Outcome Measures. —Primary: change in diastolic blood pressure from baseline to final follow-up, measured by blinded observers. Secondary: changes in systolic blood pressure and intervention compliance measures. Results. —Weight reduction intervention produced weight loss of 3.9 kg (P .05). Conclusions. —Weight reduction is the most effective of the strategies tested for reducing blood pressure in normotensive persons. Sodium reduction is also effective. The long-term effects of weight reduction and sodium reduction, alone and in combination, require further evaluation. (JAMA. 1992;267:1213-1220)

717 citations


Cited by
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TL;DR: Since 1980, the American College of Cardiology and American Heart Association have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health.
Abstract: Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health. In 2013, the National Heart, Lung, and Blood Institute (NHLBI) Advisory

4,604 citations

Journal ArticleDOI
Frank B. Hu1
TL;DR: The rationale for studying dietary patterns is described, quantitative methods for analysing dietary patterns and their reproducibility and validity are discussed, and the available evidence regarding the relationship between major Dietary patterns and the risk of cardiovascular disease is discussed.
Abstract: Recently, dietary pattern analysis has emerged as an alternative and complementary approach to examining the relationship between diet and the risk of chronic diseases. Instead of looking at individual nutrients or foods, pattern analysis examines the effects of overall diet. Conceptually, dietary patterns represent a broader picture of food and nutrient consumption, and may thus be more predictive of disease risk than individual foods or nutrients. Several studies have suggested that dietary patterns derived from factor or cluster analysis predict disease risk or mortality. In addition, there is growing interest in using dietary quality indices to evaluate whether adherence to a certain dietary pattern (e.g. Mediterranean pattern) or current dietary guidelines lowers the risk of disease. In this review, we describe the rationale for studying dietary patterns, and discuss quantitative methods for analysing dietary patterns and their reproducibility and validity, and the available evidence regarding the relationship between major dietary patterns and the risk of cardiovascular disease.

3,383 citations

Journal ArticleDOI
TL;DR: The Task Force has summarized the most important clinical issues on coronary heart disease prevention on which there is good agreement in order to give cardiologists and physicians, and other health care professionals, the best possible advice to facilitate their work on coronaryHeart disease prevention.

1,446 citations