E
Edgar Buhl
Researcher at University of Bristol
Publications - 30
Citations - 751
Edgar Buhl is an academic researcher from University of Bristol. The author has contributed to research in topics: Circadian rhythm & Circadian clock. The author has an hindex of 13, co-authored 27 publications receiving 572 citations. Previous affiliations of Edgar Buhl include Leipzig University & University of Exeter.
Papers
More filters
Journal ArticleDOI
Drosophila Ionotropic Receptor 25a mediates circadian clock resetting by temperature.
Chenghao Chen,Edgar Buhl,Min Xu,Vincent Croset,Johanna S. Rees,Kathryn S. Lilley,Richard Benton,James J L Hodge,Ralf Stanewsky +8 more
TL;DR: It is shown that Drosophila Ionotropic Receptor 25a (IR25a) is required for behavioural synchronization to low-amplitude temperature cycles, and it is proposed that IR25a is part of an input pathway to the circadian clock that detects small temperature differences.
Journal ArticleDOI
A Neural Network Underlying Circadian Entrainment and Photoperiodic Adjustment of Sleep and Activity in Drosophila.
Matthias Schlichting,Pamela Menegazzi,Katharine R. Lelito,Zepeng Yao,Edgar Buhl,Elena Dalla Benetta,Andrew Bahle,Jennifer Denike,James J L Hodge,Charlotte Helfrich-Förster,Orie T. Shafer +10 more
TL;DR: The results establish that input from the HB eyelets differentially impacts the physiology of neuronal subgroups, and provide a mechanistic model of light transduction and integration into the circadian system, identifying new and unexpected network motifs within the circadian clock neuron network.
Journal ArticleDOI
Drosophila PINK1 and parkin loss-of-function mutants display a range of non-motor Parkinson's disease phenotypes.
TL;DR: This study examined memory performance and circadian rhythms in flies with loss-of-function mutations in two PD genes: PINK1 and parkin, and found learning and memory abnormalities in both mutant genotypes, as well as a weakening of circadian rhythms that is underpinned by electrophysiological changes in clock neurons.
Journal ArticleDOI
Can Simple Rules Control Development of a Pioneer Vertebrate Neuronal Network Generating Behavior
Alan Roberts,Deborah Conte,Mike Hull,Mike Hull,Robert Merrison-Hort,Abul Kalam Al Azad,Edgar Buhl,Roman Borisyuk,Stephen R. Soffe +8 more
TL;DR: This functioning model represents the most complete reconstruction of a vertebrate neuronal network that can reproduce the complex, rhythmic behavior of a whole animal and validate the novel developmental strategy for generating realistic networks with individual neuron- and synapse-level resolution.
Journal ArticleDOI
A muscarinic cholinergic mechanism underlies activation of the central pattern generator for locust flight
TL;DR: It is speculated that muscarinic activation coupled to aminergic facilitation may be a general feature of behavioural control in insects for ensuring conditional recruitment of individual motor programs in accordance with momentary adaptive requirements.