Author
Edgar V. Allen
Bio: Edgar V. Allen is an academic researcher from University of Rochester. The author has contributed to research in topics: Embolism & Psychasthenia. The author has an hindex of 17, co-authored 34 publications receiving 1592 citations.
Topics: Embolism, Psychasthenia, Sympathectomy, Venous thrombosis, Neurasthenia
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01 Jan 1972
TL;DR: In this paper, the authors present an organized approach to diagnosis and treatment in connection with problems of the ageing spine, including biochemical, biomechanical and histologic aspects of spinal ageing and degeneration.
Abstract: Presents an organized approach to diagnosis and treatment in connection with problems of the ageing spine. Current concepts of the biochemical, biomechanical and histologic aspects of spinal ageing and degeneration are included.
423 citations
272 citations
TL;DR: There is little in the literature on abnormal localized depositions of body fat to clarify the syndrome of lipedema of the legs, but two of us (E. V. and E. A. H.) described it in 1940.
Abstract: Excerpt There is little in the literature on abnormal localized depositions of body fat to clarify the syndrome of lipedema of the legs which two of us (E. V. A. and E. A. H.) described in 1940.1Co...
188 citations
TL;DR: Orthostatic hypotension should be suspected whenever a patient has exhaustion in the morning which lessens during the day, whenever weakness, dimness of vision or syncope occurs on assumption of the erect posture and disappears on lying down, whenever episodes of syncope are inadequately explained and whenever there is diminished sweating.
Abstract: Orthostatic hypotension is characterized chiefly by a sharp decrease in blood pressure when a patient afflicted with it stands. The blood pressure is ordinarily normal when the patient lies. If the blood pressure decreases to a low level, weakness and syncope result. Other relevant signs or symptoms are deficient sweating, either localized or generalized, secretion of larger amounts of urine when the patient is recumbent than when he is erect and in some cases a failure of the pulse rate to increase markedly when the patient assumes the erect posture. Orthostatic hypotension should be suspected whenever a patient has exhaustion in the morning which lessens during the day, whenever weakness, dimness of vision or syncope occurs on assumption of the erect posture and disappears on lying down, whenever episodes of syncope are inadequately explained and whenever there is diminished sweating. This condition has been considered by some to be the
129 citations
TL;DR: It was recognized early that if the hemorrhagic manifestations had not proceeded too far the hemorrhage could be controlled by withdrawal of the spoiled hay from the diet or by the injection of freshly drawn blood serum of healthy animals.
Abstract: It has been known for many years by veterinarians and cattle raisers that cattle fairly frequently and for no apparent reason bleed considerably and perhaps fatally. Studies of this condition were made originally and independently in 1921 by Schofield1in Canada and by Roderick2in this country. They determined that this hemorrhagic disease arises from eating improperly cured hay or silage made from the common sweet clovers. It was recognized early that if the hemorrhagic manifestations had not proceeded too far the hemorrhage could be controlled by withdrawal of the spoiled hay from the diet or by the injection of freshly drawn blood serum of healthy animals.3At first it was thought that the liver was damaged by the ingested spoiled hay, but this could not be confirmed by Roderick. However, he noted that the delayed coagulability of the blood involved a reduction in the prothrombin content
81 citations
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TL;DR: The establishment of a vascular supply is required for organ development and differentiation as well as for tissue repair and reproductive functions in the adult.
Abstract: The establishment of a vascular supply is required for organ development and differentiation as well as for tissue repair and reproductive functions in the adult1 Neovascularization (angiogenesis) is also implicated in the pathogenesis of a number of disorders These include: proliferative retinopathies, age-related macular degeneration, tumors, rheumatoid arthritis, and psoriasis1,2 A strong correlation has been noted between density of microvessels in primary breast cancers and their nodal metastases and patient survival3 Similarly, a correlation has been reported between vascularity and invasive behavior in several other tumors4–6
4,603 citations
1,238 citations
TL;DR: Table of contents Preamble Scope of the document: Classification, epidemiology and prognosis and diagnosis strategy of evaluation, method, and findings.
Abstract: Table of contents Preamble Scope of the document 1256 Method 1257 Part 1. Classification, epidemiology and prognosis Definition 1258 Brief overview of pathophysiology of syncope 1258 Classification 1259 Epidemiological considerations 1259 Prognostic stratification: identification of factors predictive of adverse outcome 1260 Part 2. Diagnosis Strategy of evaluation (flow chart) 1262 Initial evaluation (history, physical examination, baseline electrocardiogram) 1264 Echocardiogram 1266 Carotid sinus massage 1266 Tilt testing 1268 Electrocardiographic monitoring (non-invasive and invasive) 1271 Electrophysiological testing 1273 ATP test 1277 Ventricular signal-averaged electrocardiogram 1278 Exercise testing 1278 Cardiac catheterization and angiography 1279 Neurological and psychiatric evaluation 1279 Diagnostic yield and prevalence of causes of syncope 1282
1,046 citations
TL;DR: A full understanding of the natural history of pulmonary embolism is elusive at the present time because many basic facts are either uncertain or unknown as mentioned in this paper, which makes it very difficult to classify the primary cause of death in patients in whom pulmonary embolness occurs as a fatal complication of other diseases.
978 citations
TL;DR: New guidelines for the management of patients with supraventricular arrhythmias are introduced and recommended for use in combination with standard clinical practice.
Abstract: ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias--executive summary : a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Arrhythmias).
966 citations