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Edmond Rambod

Bio: Edmond Rambod is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Vortex ring & Microbubbles. The author has an hindex of 16, co-authored 37 publications receiving 2660 citations. Previous affiliations of Edmond Rambod include Oregon Health & Science University & Fresenius Medical Care.

Papers
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Journal ArticleDOI
TL;DR: The formation of vortex rings generated through impulsively started jets is studied experimentally in this paper, where the velocity and vorticity field of the leading vortex ring formed is disconnected from that of the trailing jet.
Abstract: The formation of vortex rings generated through impulsively started jets is studied experimentally. Utilizing a piston/cylinder arrangement in a water tank, the velocity and vorticity fields of vortex rings are obtained using digital particle image velocimetry (DPIV) for a wide range of piston stroke to diameter (L/D) ratios. The results indicate that the flow field generated by large L/D consists of a leading vortex ring followed by a trailing jet. The vorticity field of the leading vortex ring formed is disconnected from that of the trailing jet. On the other hand, flow fields generated by small stroke ratios show only a single vortex ring. The transition between these two distinct states is observed to occur at a stroke ratio of approximately 4, which, in this paper, is referred to as the ‘formation number’. In all cases, the maximum circulation that a vortex ring can attain during its formation is reached at this non-dimensional time or formation number. The universality of this number was tested by generating vortex rings with different jet exit diameters and boundaries, as well as with various non-impulsive piston velocities. It is shown that the ‘formation number’ lies in the range of 3.6–4.5 for a broad range of flow conditions. An explanation is provided for the existence of the formation number based on the Kelvin–Benjamin variational principle for steady axis-touching vortex rings. It is shown that based on the measured impulse, circulation and energy of the observed vortex rings, the Kelvin–Benjamin principle correctly predicts the range of observed formation numbers.

1,042 citations

Journal ArticleDOI
TL;DR: It is demonstrated that major aspects of cardiac function are reflected uniquely and sensitively in the optimization of vortex formation in the blood flow during early diastole, as measured by a dimensionless numerical index.
Abstract: Heart disease remains a leading cause of death worldwide. Previous research has indicated that the dynamics of the cardiac left ventricle (LV) during diastolic filling may play a critical role in dictating overall cardiac health. Hence, numerous studies have aimed to predict and evaluate global cardiac health based on quantitative parameters describing LV function. However, the inherent complexity of LV diastole, in its electrical, muscular, and hemodynamic processes, has prevented the development of tools to accurately predict and diagnose heart failure at early stages, when corrective measures are most effective. In this work, it is demonstrated that major aspects of cardiac function are reflected uniquely and sensitively in the optimization of vortex formation in the blood flow during early diastole, as measured by a dimensionless numerical index. This index of optimal vortex formation correlates well with existing measures of cardiac health such as the LV ejection fraction. However, unlike existing measures, this previously undescribed index does not require patient-specific information to determine numerical index values corresponding to normal function. A study of normal and pathological cardiac health in human subjects demonstrates the ability of this global index to distinguish disease states by a straightforward analysis of noninvasive LV measurements.

315 citations

Patent
09 Feb 2007
TL;DR: A continuous renal replacement therapy (CRRT) device adapted to be worn on a portion of the body of a patient is described in this paper, which operates on rechargeable batteries for more than 5 hours.
Abstract: A continuous renal replacement therapy (CRRT) device adapted to be worn on a portion of the body of a patient. The CRRT device is worn by the patient and operates on rechargeable batteries for more than 5 hours. Dialysate is used to remove impurities from the blood. The dialysate is recycled and refreshed by a filter section. Less than one liter of dialysate is required to circulate through the wearable CRRT device.

191 citations

Journal ArticleDOI
TL;DR: The formation time scale of axisymmetric vortex rings is studied numerically for relatively long discharge times in this paper, and it is shown that the scaled circulation of the pinched off vortex is relatively insensitive to the details of the formation process, such as the velocity programme, velocity profile, vortex generator geometry and the Reynolds number.
Abstract: The formation time scale of axisymmetric vortex rings is studied numerically for relatively long discharge times. Experimental findings on the existence and universality of a formation time scale, referred to as the `formation number', are confirmed. The formation number is indicative of the time at which a vortex ring acquires its maximal circulation. For vortex rings generated by impulsive motion of a piston, the formation number was found to be approximately four, in very good agreement with experimental results. Numerical extensions of the experimental study to other cases, including cases with thick shear layers, show that the scaled circulation of the pinched-off vortex is relatively insensitive to the details of the formation process, such as the velocity programme, velocity profile, vortex generator geometry and the Reynolds number. This finding might also indicate that the properly scaled circulation of steady vortex rings varies very little. The formation number does depend on the velocity profile. Non-impulsive velocity programmes slightly increase the formation number, while non-uniform velocity profiles may decrease it significantly. In the case of a parabolic velocity profile of the discharged flow, for example, the formation number decreases by a factor as large as four. These findings indicate that a major source of the experimentally found small variations in the formation number is the different evolution of the velocity profile of the discharged flow.

188 citations

Journal ArticleDOI
TL;DR: In this article, the safety and efficiency of wearable haemodialysis devices were evaluated in patients with end-stage kidney failure and showed promising safety and efficacy results, although further studies will be necessary to confirm these results.

183 citations


Cited by
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Journal ArticleDOI
TL;DR: Current perspectives on all four of these components in thrombosis and with biomaterials and cardiovascular devices are summarized.

1,251 citations

Journal ArticleDOI
TL;DR: In this article, a review of the recent progress in flapping wing aerodynamics and aeroelasticity is presented, where it is realized that a variation of the Reynolds number (wing sizing, flapping frequency, etc.) leads to a change in the leading edge vortex (LEV) and spanwise flow structures, which impacts the aerodynamic force generation.

877 citations

Journal ArticleDOI
TL;DR: In this article, the principal mechanism for producing propulsive and transient forces in oscillating flexible bodies and fins in water, the formation and control of large-scale vortices, was identified.
Abstract: Interest in novel forms of marine propulsion and maneuvering has sparked a number of studies on unsteadily operating propulsors. We review recent experimental and theoretical work identifying the principal mechanism for producing propulsive and transient forces in oscillating flexible bodies and fins in water, the formation and control of large-scale vortices. Connection with studies on live fish is made, explaining the observed outstanding fish agility.

816 citations

Patent
07 Aug 2008
TL;DR: In this article, the authors describe a system and methods for obtaining and acting upon information indicative of circulatory health and related phenomena in human beings or other subjects. But they do not discuss the application of this information in medical applications.
Abstract: Systems and methods are described for obtaining and acting upon information indicative of circulatory health and related phenomena in human beings or other subjects.

496 citations

Patent
Bryan Greener1
20 Nov 2008
TL;DR: In this paper, the authors described an apparatus for the application of topical negative pressure therapy to a wound site, consisting of a wound contacting element for retaining wound exudate fluid therein, wound covering element that provides a substantially airtight seal over the wound contact element and wound site; and a vacuum connection tube connecting a wound cavity to a vacuum source.
Abstract: Apparatus for the application of topical negative pressure therapy to a wound site is described, the apparatus comprising: a wound contacting element for retaining wound exudate fluid therein; a wound covering element that provides a substantially airtight seal over the wound contacting element and wound site; a vacuum connection tube connecting a wound cavity to a vacuum source; and a vacuum source connected to a distal end of the vacuum connection tube.

485 citations