E
Edward M. Behrens
Researcher at Children's Hospital of Philadelphia
Publications - 137
Citations - 7540
Edward M. Behrens is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Medicine & Macrophage activation syndrome. The author has an hindex of 36, co-authored 109 publications receiving 5266 citations. Previous affiliations of Edward M. Behrens include University of Pennsylvania.
Papers
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Journal ArticleDOI
On the Alert for Cytokine Storm: Immunopathology in COVID-19.
Lauren A. Henderson,Scott W. Canna,Grant S. Schulert,Stefano Volpi,Pui Y. Lee,Kate F. Kernan,Roberto Caricchio,Shawn A. Mahmud,Melissa M. Hazen,Olha Halyabar,Kacie J Hoyt,Joseph Han,Alexei A. Grom,Marco Gattorno,Angelo Ravelli,Fabrizio De Benedetti,Edward M. Behrens,Randy Q. Cron,Peter A. Nigrovic +18 more
TL;DR: While studies are ongoing, extrapolating from clinical experience in cytokine storm syndromes may benefit the multidisciplinary teams caring for patients with severe COVID‐19.
Journal ArticleDOI
2016 Classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: A European league against Rheumatism/American college of Rheumatology/Paediatric rheumatology international trials organisation collaborative initiative
Angelo Ravelli,Francesca Minoia,Sergio Davì,AnnaCarin Horne,Francesca Bovis,Angela Pistorio,Maurizio Aricò,Tadej Avcin,Edward M. Behrens,Fabrizio De Benedetti,Lisa Filipovic,Alexei A. Grom,Jan-Inge Henter,Norman T. Ilowite,Michael B. Jordan,Raju Khubchandani,Toshiyuki Kitoh,Kai Lehmberg,Daniel J. Lovell,Paivi Miettunen,Kim E. Nichols,Seza Ozen,Jana Pachlopnik Schmid,Athimalaipet V Ramanan,Ricardo Russo,Rayfel Schneider,Gary Sterba,Yosef Uziel,Carol A. Wallace,Carine Wouters,Nico M Wulffraat,Erkan Demirkaya,Hermine I. Brunner,Alberto Martini,Nicolino Ruperto,Randy Q. Cron +35 more
TL;DR: Criteria for the classification of macrophage activation syndrome (MAS) in patients with systemic juvenile idiopathic arthritis (JIA) is developed.
Journal Article
Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis.
TL;DR: Occult MAS appears to be common in patients with SJIA who undergo BMA, which suggests that macrophage activation may be integral to the pathogenesis of SJIA, with implications for treatment.
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Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment.
TL;DR: There has been remarkable progress in the use of anti-pro-inflammatory cytokine therapy, particularly against interleukin-1, in the treatment of secondary forms of MAS, such as in sJIA.
Journal ArticleDOI
Multisystem Inflammatory Syndrome in Children During the Coronavirus 2019 Pandemic: A Case Series.
Kathleen Chiotos,Kathleen Chiotos,Hamid Bassiri,Hamid Bassiri,Edward M. Behrens,Allison M Blatz,Joyce C. Chang,Joyce C. Chang,Caroline Diorio,Julie C. Fitzgerald,Julie C. Fitzgerald,Alexis A. Topjian,Alexis A. Topjian,Audrey R. Odom John,Audrey R. Odom John +14 more
TL;DR: Key findings of this syndrome include fever, diarrhea, shock, and variable presence of rash, conjunctivitis, extremity edema, and mucous membrane changes.