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Edward Post
Researcher at VU University Medical Center
Publications - 13
Citations - 935
Edward Post is an academic researcher from VU University Medical Center. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 3, co-authored 3 publications receiving 633 citations.
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Journal ArticleDOI
RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics
Myron G. Best,Nik Sol,Irsan E. Kooi,Jihane Tannous,Bart A. Westerman,François Rustenburg,Pepijn Schellen,Heleen Verschueren,Edward Post,Jan Koster,Bauke Ylstra,Najim Ameziane,Josephine C. Dorsman,Egbert F. Smit,Henk M.W. Verheul,David P. Noske,Jaap C. Reijneveld,R. Jonas A. Nilsson,R. Jonas A. Nilsson,Bakhos A. Tannous,Pieter Wesseling,Pieter Wesseling,Thomas Wurdinger,Thomas Wurdinger +23 more
TL;DR: The results indicate that blood platelets provide a valuable platform for pan-cancer, multiclass cancer, and companion diagnostics, possibly enabling clinical advances in blood-based “liquid biopsies”.
Journal ArticleDOI
Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets
Myron G. Best,Nik Sol,Sjors G J G In 't Veld,Adrienne Vancura,Mirte Muller,Anna Larissa N. Niemeijer,Aniko V. Fejes,Aniko V. Fejes,Lee Ann Tjon Kon Fat,Anna E. Huis In ‘t Veld,Cyra E. Leurs,Tessa Y S Le Large,Laura L. Meijer,Irsan E. Kooi,François Rustenburg,Pepijn Schellen,Heleen Verschueren,Edward Post,Laurine E. Wedekind,Jillian Bracht,Michelle Esenkbrink,Leon J Wils,Francesca Favaro,Jilian D. Schoonhoven,Jihane Tannous,Hanne Meijers-Heijboer,Geert Kazemier,Elisa Giovannetti,Jaap C. Reijneveld,Sander Idema,Joep Killestein,Michal Heger,Saskia C.A. de Jager,Rolf T. Urbanus,Imo E. Hoefer,Gerard Pasterkamp,Christine Mannhalter,Jose Gomez-Arroyo,Harm Jan Bogaard,David P. Noske,W. Peter Vandertop,Daan van den Broek,Bauke Ylstra,R. Jonas A. Nilsson,R. Jonas A. Nilsson,Pieter Wesseling,Pieter Wesseling,Niki Karachaliou,Rafael Rosell,Elizabeth Lee-Lewandrowski,Kent B. Lewandrowski,Bakhos A. Tannous,Adrianus J. de Langen,Egbert F. Smit,Egbert F. Smit,Michel M van den Heuvel,Michel M van den Heuvel,Thomas Wurdinger,Thomas Wurdinger +58 more
TL;DR: It is demonstrated that particle-swarm optimization-enhanced algorithms enable efficient selection of RNA biomarker panels from platelet RNA-sequencing libraries to diagnose cancer from TEPs, suggesting that swarm intelligence may also benefit the optimization of diagnostics readout of other liquid biopsy biosources.
Journal ArticleDOI
Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma
Nik Sol,Sjors G J G In 't Veld,Adrienne Vancura,Maud Tjerkstra,Cyra E. Leurs,François Rustenburg,Pepijn Schellen,Heleen Verschueren,Edward Post,Kenn Zwaan,Jip Ramaker,Laurine E. Wedekind,Jihane Tannous,Bauke Ylstra,Joep Killestein,Farrah J. Mateen,Sander Idema,Philip C. De Witt Hamer,Anna C. Navis,William P.J. Leenders,Ann Hoeben,B. Moraal,David P. Noske,W. Peter Vandertop,R. Jonas A. Nilsson,R. Jonas A. Nilsson,Bakhos A. Tannous,Pieter Wesseling,Jaap C. Reijneveld,Myron G. Best,Thomas Wurdinger +30 more
TL;DR: Tumor-educated platelets (TEPs) have potential as a minimally invasive biosource for blood-based diagnostics and monitoring of glioblastoma patients and could be used to distinguish false positive progression from true progression.
Journal ArticleDOI
Detection and localization of early- and late-stage cancers using platelet RNA.
Sjors G J G In 't Veld,Mohammad Arkani,Edward Post,Mafalda Antunes-Ferreira,Silvia D’Ambrosi,Daan C L Vessies,Lisa Vermunt,Adrienne Vancura,Mirte Muller,Anna-Larissa N. Niemeijer,Jihane Tannous,Laura L. Meijer,Tessa Y S Le Large,Giulia Mantini,Niels Wondergem,K.M. Heinhuis,Sandra van Wilpe,A.J. Smits,Esther E.E. Drees,Eva Roos,Cyra E. Leurs,Lee Ann Tjon Kon Fat,Ewoud J. van der Lelij,Govert Dwarshuis,Maarten J. Kamphuis,Lisanne E Visser,Romée Harting,Annemijn Gregory,Markus Schweiger,Laurine E. Wedekind,J. Ramaker,Kenn Zwaan,Heleen Verschueren,Idris Bahce,Adrianus J. de Langen,Egbert F. Smit,Michel M. van den Heuvel,Koen J. Hartemink,Marijke J.E. Kuijpers,Mirjam G.A. oude Egbrink,Arjan W. Griffioen,R.L. Rossel,T. Jeroen N. Hiltermann,Elizabeth Lee-Lewandrowski,Kent B. Lewandrowski,Philip C. De Witt Hamer,Mathilde C.M. Kouwenhoven,Jaap C. Reijneveld,William P.J. Leenders,Ann Hoeben,Irma M. Verdonck-de Leeuw,C. René Leemans,Robert J. Baatenburg de Jong,Chris H.J. Terhaard,Robert P. Takes,Johannes A. Langendijk,Saskia C.A. de Jager,Adriaan O. Kraaijeveld,Gerard Pasterkamp,Minke Smits,Jack A. Schalken,Sylwia Łapińska-Szumczyk,Anna Łojkowska,Anna J. Zaczek,Henk M. Lokhorst,N. W. C. J. van de Donk,Inger S. Nijhof,Henk-Jan Prins,Josée M. Zijlstra,Sander Idema,Johannes C. Baayen,Charlotte E. Teunissen,Joep Killestein,Marc G. Besselink,Lindsay Brammen,Thomas Bachleitner-Hofmann,Farrah J. Mateen,John T. M. Plukker,Michal Heger,Quirijn de Mast,Ton Lisman,D. Michiel Pegtel,Harm Jan Bogaard,Jacek Jassem,Anna Supernat,Niven Mehra,Winald R. Gerritsen,Cornelis D. de Kroon,Christianne A. R. Lok,Jürgen Piek,Neeltje Steeghs,Winan J. van Houdt,Ruud H. Brakenhoff,Gabe S. Sonke,Henk M.W. Verheul,Elisa Giovannetti,Geert Kazemier,Siamack Sabrkhany,Ed Schuuring,Erik A. Sistermans,Rob M. F. Wolthuis,Hanne Meijers-Heijboer,Josephine C. Dorsman,Cees B.M. Oudejans,Bauke Ylstra,Bart A. Westerman,D. Van Den Broek,Danijela Koppers-Lalic,Pieter Wesseling,R. Jonas A. Nilsson,W. Peter Vandertop,David P. Noske,Bakhos A. Tannous,Nik Sol,Myron G. Best,Thomas Wurdinger +115 more
TL;DR: In this article , a tumor-educated platelet (TEP) RNA-based blood tests enable the detection of 18 cancer types with 99% specificity in asymptomatic controls.
Journal ArticleDOI
Platelet RNA enables accurate detection of ovarian cancer: an intercontinental, biomarker identification study
Yue-Yue Gao,Chun-Jie Liu,Huayi Li,Xiaomin Xiong,Gui-Ling Li,Sjors G J G In 't Veld,Guangyao Cai,Gui-Yan Xie,Shaoqing Zeng,Yuan Wu,Jianhua Chi,Jia-Hao Liu,Qiong Zhang,Xiaofei Jiao,Lin-Li Shi,Wanrong Lu,Weiguo Lv,Xing-Sheng Yang,Jürgen Piek,Cornelis D. de Kroon,C. A. R. Lok,Anna Supernat,Sylwia Łapińska-Szumczyk,Anna Łojkowska,Anna J. Zaczek,Jacek Jassem,Bakhos A. Tannous,Nik Sol,Edward Post,Myron G. Best,Beihua Kong,Xing Xie,Ding Ma,Thomas Wurdinger,An-Yuan Guo,Qinglei Gao +35 more
TL;DR: In this paper , the authors used tumor-educated platelets (TEPs) to detect early stage, borderline, non-epithelial diseases and to discriminate ovarian cancer from endometriosis.