Edward S. Grood

Bio: Edward S. Grood is an academic researcher from University of Cincinnati. The author has contributed to research in topics: Anterior cruciate ligament & Ligament. The author has an hindex of 54, co-authored 98 publications receiving 17215 citations.

A Joint Coordinate System for the Clinical Description of Three-Dimensional Motions: Application to the Knee

Abstract: The experimental study of joint kinematics in three dimensions requires the description and measurement of six motion components. An important aspect of any method of description is the ease with which it is communicated to those who use the data. This paper presents a joint coordinate system that provides a simple geometric description of the three-dimensional rotational and translational motion between two rigid bodies. The coordinate system is applied to the knee and related to the commonly used clinical terms for knee joint motion. A convenient characteristic of the coordinate system shared by spatial linkages is that large joint displacements are independent of the order in which the component translations and rotations occur.

Biomechanical analysis of human ligament grafts used in knee-ligament repairs and reconstructions.

Abstract: Virtually all types of collagenous tissues have been transferred in and around the knee joint for intra-articular and extra-articular ligament reconstructions. However, the mechanical properties (in particular, strength) of such grafts have not been determined in tissues from young adult donors, where age and disuse-related effects have been excluded. To provide this information, we subjected ligament graft tissues to high-strain-rate failure tests to determine their strength and elongation properties. The results were compared with the mechanical properties of anterior cruciate ligaments from a similar young-adult donor population. The study indicated that some graft tissues used in ligament reconstructions are markedly weak and therefore are at risk for elongation and failure at low forces. Grafts utilizing prepatellar retinacular tissues (as in certain anterior-cruciate reconstructions) and others in which a somewhat narrow width of fascia lata or distal iliotibial tract is utilized are included in this at-risk group. Wider grafts from the iliotibial tract or fascia lata would of course proportionally increase ultimate strength. The semitendinosus and gracilis tendons are stronger, having 70 and 49 per cent, respectively, of the initial strength of anterior cruciate ligaments. The bone-patellar tendon-bone graft (fourteen to fifteen millimeters wide, medial or central portion) was the strongest, with a mean strength of 159 to 168 per cent of that of anterior cruciate ligaments. Patellar tendon-bone units, based on grip-to-grip motions, were found to be three to four times stiffer than similarly gripped anterior cruciate ligaments, while gracilis and semitendinosus tendon preparations had values that were nearly identical to those of anterior cruciate ligaments.(ABSTRACT TRUNCATED AT 250 WORDS)

The strength of the anterior cruciate ligament in humans and Rhesus monkeys.

Abstract: The mechanical properties of anterior cruciate bone-ligament-bone specimens from humans and rhesus monkeys were determined in tension to failure under high strain-rate conditions. The age range of the human specimens was from sixteen to eighty-six years. The values fro human specimens obtained from young adults with regard to elastic modulus, ultimate tensile stress, and strain energy to failure were approximately two to three times those for specimens from humans in the sixth decade and older. The major mode of failure was ligament disruption in the specimens from young adult humans and avulsion of bone beneath the ligament insertion site in the specimens from older humans. The difference in mode of failure correlated with histological observations of decreased bone mass at the site of ligament attachment in the specimens from older humans. Rhesus monkey specimens had higher values for elastic modulus, failure stress, and strain energy. Significant reductions in strength and stiffness properties of ligament units were shown to occur with advancing age to a greater degree than expected. All experiments in which specimens from older human cadavera are used should be interpreted with caution when the results are applied to mechanisms of ligament failure for younger or athletic individuals.

Arthroscopy in acute traumatic hemarthrosis of the knee. Incidence of anterior cruciate tears and other injuries.

Abstract: In a prospective study, all injured knees that had traumatic hemarthrosis and absent or negligible instability on clinical examination underwent arthroscopy and examination under anesthesia. Eighty-five knees (eighty-three patients) were examined over a 125-week period. Some degree of disruption of the anterior cruciate ligament was found in sixty-one (72 per cent) of the knees (a partial tear in 28 per cent and a complete tear in 44 per cent), frequently associated with an injury of varying severity to other joint structures. These included minor ligament sprains without laxity in 41 per cent, a major associated ligament injury in 21 per cent, meniscal tears in 62 per cent (partial in 30 per cent and complete in 70 per cent), and a femoral chondral fracture or surface defect in 20 per cent. A popping sensation at injury occurred in 33 per cent of knees with a normal anterior cruciate ligament and in 36 per cent of those with a disruption. One-third of the knees had no to slight pain at the time of injury. The anterior drawer test without anesthesia was positive in only 24 per cent of the knees with a torn anterior cruciate ligament. We concluded that: (1) a traumatic hemarthrosis indicates a significant knee injury; (2) examination under anesthesia plus arthroscopy allows a more accurate diagnosis of injury to joint structures; and (3) such data are required for a rational treatment program to be outlined.

I and i

Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation

Abstract: Background Full-thickness defects of articular cartilage in the knee have a poor capacity for repair. They may progress to osteoarthritis and require total knee replacement. We performed autologous chondrocyte transplantation in 23 people with deep cartilage defects in the knee. Methods The patients ranged in age from 14 to 48 years and had full-thickness cartilage defects that ranged in size from 1.6 to 6.5 cm2. Healthy chondrocytes obtained from an uninvolved area of the injured knee during arthroscopy were isolated and cultured in the laboratory for 14 to 21 days. The cultured chondrocytes were then injected into the area of the defect. The defect was covered with a sutured periosteal flap taken from the proximal medial tibia. Evaluation included clinical examination according to explicit criteria and arthroscopic examination with a biopsy of the transplantation site. Results Patients were followed for 16 to 66 months (mean, 39). Initially, the transplants eliminated knee locking and reduced pain and s...

Biomechanical Measures of Neuromuscular Control and Valgus Loading of the Knee Predict Anterior Cruciate Ligament Injury Risk in Female Athletes A Prospective Study

Abstract: BackgroundFemale athletes participating in high-risk sports suffer anterior cruciate ligament injury at a 4- to 6-fold greater rate than do male athletes.HypothesisPrescreened female athletes with subsequent anterior cruciate ligament injury will demonstrate decreased neuromuscular control and increased valgus joint loading, predicting anterior cruciate ligament injury risk.Study DesignCohort study; Level of evidence, 2.MethodsThere were 205 female athletes in the high-risk sports of soccer, basketball, and volleyball prospectively measured for neuromuscular control using 3-dimensional kinematics (joint angles) and joint loads using kinetics (joint moments) during a jump-landing task. Analysis of variance as well as linear and logistic regression were used to isolate predictors of risk in athletes who subsequently ruptured the anterior cruciate ligament.ResultsNine athletes had a confirmed anterior cruciate ligament rupture; these 9 had significantly different knee posture and loading compared to the 196 ...