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Ekaterina B. Kuznetsova
Researcher at I.M. Sechenov First Moscow State Medical University
Publications - 37
Citations - 429
Ekaterina B. Kuznetsova is an academic researcher from I.M. Sechenov First Moscow State Medical University. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 9, co-authored 31 publications receiving 258 citations. Previous affiliations of Ekaterina B. Kuznetsova include Russian Academy.
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Journal ArticleDOI
Epigenetic Changes in the Pathogenesis of Rheumatoid Arthritis.
Marina V. Nemtsova,Dmitry V. Zaletaev,Irina V. Bure,Dmitry S. Mikhaylenko,Ekaterina B. Kuznetsova,Ekaterina A. Alekseeva,Marina I. Beloukhova,Andrei A. Deviatkin,Alexander N. Lukashev,Andrey A. Zamyatnin,Andrey A. Zamyatnin +10 more
TL;DR: This review focuses on the role of multiple epigenetic factors in the pathogenesis and progression of the disease, not only in synovial fibroblasts, immune cells, but also in the peripheral blood of patients with RA, which clearly shows their high diagnostic potential and promising targets for therapy in the future.
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Clinical relevance of somatic mutations in main driver genes detected in gastric cancer patients by next-generation DNA sequencing
Marina V. Nemtsova,A.I. Kalinkin,Ekaterina B. Kuznetsova,Irina V. Bure,Ekaterina A. Alekseeva,I. I. Bykov,T. V. Khorobrykh,Dmitry S. Mikhaylenko,Alexander S Tanas,Sergey I. Kutsev,Dmitry V. Zaletaev,Vladimir V Strelnikov +11 more
TL;DR: The results confirm that the detection of mutations in the main driver genes may have a significant prognostic value for GC patients and provide an independent GC-related set of clinical and molecular genetic data.
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Methylation of the BIN1 gene promoter CpG island associated with breast and prostate cancer
Ekaterina B. Kuznetsova,T. V. Kekeeva,Larin Ss,Valeria V Zemlyakova,Anastasiya V Khomyakova,O. V. Babenko,Marina V. Nemtsova,D. V. Zaletayev,Vladimir V Strelnikov +8 more
TL;DR: BIN1 promoter CpG island is composed of two parts differing drastically in the methylation patterns in cancer, which appears to be a common feature of cancer related genes and demands further functional significance exploration.
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Genetic Polymorphisms Associated with Rheumatoid Arthritis Development and Antirheumatic Therapy Response.
Dmitry S. Mikhaylenko,Marina V. Nemtsova,Irina V. Bure,Ekaterina B. Kuznetsova,Ekaterina A. Alekseeva,Vadim V. Tarasov,Alexander N. Lukashev,Marina I. Beloukhova,Andrei A. Deviatkin,Andrey A. Zamyatnin,Andrey A. Zamyatnin +10 more
TL;DR: The review has two purposes: to summarise the data on RA candidate genes and the increased disease risk associated with these alleles in various populations and to describe how the genetic variants can be used in the selection of drugs for the treatment of RA.
Journal ArticleDOI
DNA methylation markers panel can improve prediction of response to neoadjuvant chemotherapy in luminal B breast cancer
Vladimir O. Sigin,A.I. Kalinkin,Ekaterina B. Kuznetsova,Olga A Simonova,Galina G. Chesnokova,Nikolai V. Litviakov,Elena M. Slonimskaya,Matvey M. Tsyganov,M.K. Ibragimova,Ilya V. Volodin,Ilya I. Vinogradov,Maksim I. Vinogradov,Igor Y. Vinogradov,Sergey I. Kutsev,Vladimir V Strelnikov,Dmitry V. Zaletaev,Alexander S Tanas +16 more
TL;DR: This work has developed multiplex methylation sensitive restriction enzyme PCR (MSRE-PCR) protocol for determining the methylation status of 10 genes that distinguish BC samples with different NACT response.