Elaine Gutierrez

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The development of chelators as unique agents for cancer treatment is discussed, demonstrating that this class of agents have multiple molecular targets and act by various mechanisms.

TL;DR: This study investigates how the novel anti-tumor agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes MDR through utilization of lysosomal Pgp transport activity.

TL;DR: It is demonstrated that Dp44mT can overcome the prosurvival activity of autophagy in cancer cells by utilizing this process to potentiate cell death.